DNA damage foci: Meaning and significance

K Rothkamm, S Barnard, J Moquet… - Environmental and …, 2015 - Wiley Online Library
The discovery of DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and
the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a …

The comet assay in animal models: From bugs to whales–(Part 1 Invertebrates)

G Gajski, B Žegura, C Ladeira, B Pourrut… - … Research/Reviews in …, 2019 - Elsevier
The comet assay, also called single cell gel electrophoresis, is a sensitive, rapid and low-
cost technique for quantifying and analysing DNA damage and repair at the level of …

Cytostatic drugs and metabolites in municipal and hospital wastewaters in Spain: filtration, occurrence, and environmental risk

N Negreira, ML de Alda, D Barceló - Science of the total environment, 2014 - Elsevier
Concerns about cytostatic anticancer drugs in the environment are increasing, mainly due to
the lack of knowledge about the fate and impact of these cytotoxic compounds in the water …

Epigenetic inactivation of tumour suppressor coding and non-coding genes in human cancer: an update

P Llinas-Arias, M Esteller - Open biology, 2017 - royalsocietypublishing.org
Cancer cells undergo many different alterations during their transformation, including
genetic and epigenetic events. The controlled division of healthy cells can be impaired …

Synthesis, characterization and discovery of multiple anticancer mechanisms of dibutyltin complexes based on salen-like ligands

W Tian, W Zhong, Z Yang, L Chen, S Lin, Y Li… - Journal of Inorganic …, 2024 - Elsevier
A series of novel dibutyltin complexes based on salen-like ligands (S01–S03) were
synthesized and characterized using ultraviolet-visible spectra, infrared spectra, 1 H, 13 C …

Growth, reproduction and biochemical toxicity of chlorantraniliprole in soil on earthworms (Eisenia fetida)

T Liu, X Wang, D Chen, Y Li, F Wang - Ecotoxicology and Environmental …, 2018 - Elsevier
Diamide insecticides have become the fourth most commonly used insecticide class in the
world. Chlorantraniliprole (CAP) is a first-generation diamide insecticide with broad …

Forgotten public health impacts of cancer–an overview

S Viegas, C Ladeira, A Costa-Veiga… - Archives of Industrial …, 2017 - sciendo.com
Cancer is one of the diseases of greatest concern in developed countries and much effort
has been invested in discovering and developing therapeutics for curing cancer. Despite the …

Differential effects of pesticides on dioxin receptor signaling and p53 activation

M Fauteux, N Côté, S Bergeron, A Maréchal… - Scientific Reports, 2023 - nature.com
As modern agricultural practices increase their use of chemical pesticides, it is inevitable
that we will find a number of these xenobiotics within drinking water supplies and …

Discovery and characterization of 4-hydroxy-2-pyridone derivative sambutoxin as a potent and promising anticancer drug candidate: activity and molecular …

LN Li, L Wang, YN Cheng, ZQ Cao… - Molecular …, 2018 - ACS Publications
Sambutoxin, a representative derivative of 4-hydroxy-2-pyridone, was isolated from
Hericium alpestre for the first time in this study. The possible correlation between the …

[HTML][HTML] Effects of elevated temperature on 8-OHdG expression in the American oyster (Crassostrea virginica): Induction of oxidative stress biomarkers, cellular …

MF Rahman, MM Billah, RJ Kline… - Fish and shellfish …, 2023 - Elsevier
Global temperature is increasing due to anthropogenic activities and the effects of elevated
temperature on DNA lesions are not well documented in marine organisms. The American …