Bacterial infections cause substantial morbidity and mortality across the world and pose
serious threats to humankind. Drug resistance, especially multidrug resistance resulting from …

Quinazolinone and quinazoline have been shown different pharmacological activities,
namely anticancer, anti-inflammatory, anti-hyperlipidemia, analgesic, antihypertensive, and …

With the aim of developing multidrug solids through a tuned crystal engineering approach,
we have selected two antiurinary infective drugs, namely, nitrofurantoin (NF) and …

Abstract Coronavirus Disease 2019 (COVID-19) has infected more than thirty five million
people worldwide and caused nearly 1 million deaths as of October 2020. The …

Twelve heterocyclic compounds were prepared using the condensation of hydroxymethanol
pyrazole derivatives with different primary aminesas example 2-aminothiazole and 1 …

Abstract The quinazolin-4 (3H)-one structural motif possesses a wide spectrum of biological
activities. DNA gyrase play an important role in induction of bacterial death. It has been …

There are convincing evidences that species belonging to the Onosma genus have been
used in the treatment of various diseases for centuries. In this study, antioxidant and …

Quinazoline derivatives are potent inhibitors of human epidermal growth factor receptor
(EGFR) as anticancer agents. In this study, the cytotoxic effects of a new series of …

Novel derivatives of bisquinazolinones and bisfuramides were synthesized and tested for
their efficiency in this work. Within short reaction times (1–10 min), bisfuramide derivatives …

As of June 2020, the coronavirus disease 19 (COVID-19) caused by the 2019 new type
coronavirus (2019-nCoV) infected more than 7,000,000 people worldwide and caused the …