In recent years, numerous efforts have been made to identify reliable biomarkers useful in
migraine diagnosis and progression or associated with the response to a specific treatment …

Fibromyalgia is a complex and heterogeneous clinical syndrome, mainly characterized by
the presence of widespread pain, possibly associated with a variety of other symptoms …

Abstract Ethnopharmacological relevance Yufeng Ningxin Tablet (YNT) is a traditional
Chinese medicine formula, that has been used clinically to treat migraine for many years. It …

Background OnabotulinumtoxinA (onabotA) is approved globally for prevention of chronic
migraine; however, the classical mechanism of action of onabotA in motor and autonomic …

Objective The objective of this study was to characterize the utility of calcitonin gene–related
peptide (CGRP) and nerve growth factor (NGF) as potential biomarkers for headache and …

A case–control study including 446 workers reporting headaches (cases; 136 males and
310 females, mean age 46.71±10.84 years) and 446 age-and sex-matched colleagues …

Migraine is a pervasive neurologic disease closely related to neurogenic inflammation. The
astrocytes and microglia in the central nervous system are vital in inducing neurogenic …

Migraine (MI) is the most common neurological disease, affecting with 20% of the world
population. A subset of 25% of MI patients showcase concurrent vestibular symptoms, which …

Ephrin-B-EphB signaling can promote pain through ligand-receptor interactions between
peripheral cells, like immune cells expressing ephrin-Bs, and EphB receptors expressed by …

The Zingiberaceae family possess various phenolic compounds that have significant
systemic bioactivities in the brain, including in age-related neurodegenerative diseases …