The contribution of astrocytes to the neuroinflammatory response in multiple sclerosis and experimental autoimmune encephalomyelitis
R Brambilla - Acta neuropathologica, 2019 - Springer
Neuroinflammation is the coordinated response of the central nervous system (CNS) to
threats to its integrity posed by a variety of conditions, including autoimmunity, pathogens …
threats to its integrity posed by a variety of conditions, including autoimmunity, pathogens …
Quantifying the Metabolic Signature of Multiple Sclerosis by in vivo Proton Magnetic Resonance Spectroscopy: Current Challenges and Future Outlook in the …
Proton magnetic resonance spectroscopy (1H-MRS) offers a growing variety of methods for
querying potential diagnostic biomarkers of multiple sclerosis in living central nervous …
querying potential diagnostic biomarkers of multiple sclerosis in living central nervous …
Evidence of widespread metabolite abnormalities in Myalgic encephalomyelitis/chronic fatigue syndrome: assessment with whole-brain magnetic resonance …
Previous neuroimaging studies have detected markers of neuroinflammation in patients with
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Magnetic Resonance …
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Magnetic Resonance …
Neuroimaging techniques to assess inflammation in multiple sclerosis
S Tommasin, C Giannì, L De Giglio, P Pantano - Neuroscience, 2019 - Elsevier
Multiple Sclerosis (MS) is a chronic neurological disease that represents a leading cause of
disability in young adults and is characterized by inflammation and degeneration of both …
disability in young adults and is characterized by inflammation and degeneration of both …
[HTML][HTML] Lesion-specific metabolic alterations in relapsing-remitting multiple sclerosis via 7 T magnetic resonance spectroscopic imaging
Background Magnetic resonance spectroscopic imaging (MRSI) of the brain enables in vivo
assessment of metabolic alterations in multiple sclerosis (MS). This provides complementary …
assessment of metabolic alterations in multiple sclerosis (MS). This provides complementary …
The influence of spatial resolution on the spectral quality and quantification accuracy of whole‐brain MRSI at 1.5 T, 3T, 7T, and 9.4 T
Purpose Inhomogeneities in the static magnetic field (B0) deteriorate MRSI data quality by
lowering the spectral resolution and SNR. MRSI with low spatial resolution is also prone to …
lowering the spectral resolution and SNR. MRSI with low spatial resolution is also prone to …
7 T magnetic resonance spectroscopic imaging in multiple sclerosis: how does spatial resolution affect the detectability of metabolic changes in brain lesions?
Objectives The aim of this study was to assess the utility of increased spatial resolution of
magnetic resonance spectroscopic imaging (MRSI) at 7 T for the detection of neurochemical …
magnetic resonance spectroscopic imaging (MRSI) at 7 T for the detection of neurochemical …
Whole-brain metabolic abnormalities are associated with mobility in older adults with multiple sclerosis
Background Older adults with multiple sclerosis (MS) experience mobility impairments, but
conventional brain imaging is a poor predictor of walking abilities in this population …
conventional brain imaging is a poor predictor of walking abilities in this population …
[HTML][HTML] Atrophied brain lesion volume, a magnetic resonance imaging biomarker for monitoring neurodegenerative changes in multiple sclerosis
In order for an MRI biomarker to be a useful tool to predict disability progression or
determine conversion from relapsing to progressive disease stages, it must show an …
determine conversion from relapsing to progressive disease stages, it must show an …
Creatine and multiple sclerosis
SM Ostojic - Nutritional Neuroscience, 2022 - Taylor & Francis
Multiple sclerosis (MS) is a complex and debilitating neurodegenerative disease, with
unknown cause (s), unpredictable prognosis, and rather limited treatment options. MS is …
unknown cause (s), unpredictable prognosis, and rather limited treatment options. MS is …