[HTML][HTML] Suppression of antiviral innate immunity by sunitinib enhances oncolytic virotherapy

BK Jha, B Dong, CT Nguyen, I Polyakova… - Molecular Therapy, 2013 - cell.com
The use of lytic viruses to preferentially infect and eliminate cancer cells while sparing
normal cells is a promising experimental therapeutic approach for treating cancer. However …

Preliminary experience on the use of the Adnatest® system for detection of circulating tumor cells in prostate cancer patients

T Todenhoefer, J Hennenlotter, S Feyerabend… - Anticancer …, 2012 - ar.iiarjournals.org
Background: The Adnatest® system combines immunomagnetic enrichment of epithelial
cells with polymerase chain reaction for prostate cancer (PC)-specific transcripts for the …

Dual EGFR/HER2 inhibition sensitizes prostate cancer cells to androgen withdrawal by suppressing ErbB3

L Chen, BA Mooso, MK Jathal, A Madhav… - Clinical Cancer …, 2011 - AACR
Purpose: Patients with recurrent prostate cancer are commonly treated with androgen
withdrawal therapy (AWT); however, almost all patients eventually progress to castration …

Significant systemic therapeutic effects of high-LET immunoradiation by 212Pb-trastuzumab against prostatic tumors of androgen-independent human prostate cancer …

Z Tan, P Chen, N Schneider… - International …, 2012 - spandidos-publications.com
The purpose of this study was to determine therapeutic effects and systemic toxicity of 212Pb-
trastuzumab in an orthotopic model of human prostate cancer cells in nude mice. TCMC …

[HTML][HTML] Systematically understanding the immunity leading to CRPC progression

Z Ji, W Zhao, HK Lin, X Zhou - PLoS computational biology, 2019 - journals.plos.org
Prostate cancer (PCa) is the most commonly diagnosed malignancy and the second leading
cause of cancer-related death in American men. Androgen deprivation therapy (ADT) has …

[HTML][HTML] Prostate cancer in African American men: the effect of androgens and microRNAs on epidermal growth factor signaling

AC Nwaneri, L McBeth, TD Hinds - Hormones and Cancer, 2016 - Springer
Prostate cancer (PC) is one of the leading causes of mortality amongst elderly men in the
USA and is second only to lung cancer. African Americans (AA) are at an increased risk of …

Beyond androgen deprivation: ancillary integrative strategies for targeting the androgen receptor addiction of prostate cancer

MF McCarty, J Hejazi… - Integrative Cancer …, 2014 - journals.sagepub.com
The large majority of clinical prostate cancers remain dependent on androgen receptor (AR)
activity for proliferation even as they lose their responsiveness to androgen deprivation or …

[HTML][HTML] A Standardized Wedelia chinensis Extract Overcomes the Feedback Activation of HER2/3 Signaling upon Androgen-Ablation in Prostate Cancer

CH Tsai, SF Tzeng, SC Hsieh, CJ Tsai… - Frontiers in …, 2017 - frontiersin.org
Crosstalk between the androgen receptor (AR) and other signaling pathways in prostate
cancer (PCa) severely affects the therapeutic outcome of hormonal therapy. Although anti …

Target acquired: progress and promise of targeted therapeutics in the treatment of prostate cancer

R Stuchbery, NJ Kurganovs, PJ McCoy… - Current Cancer Drug …, 2015 - ingentaconnect.com
Cancer is fundamentally a genomic disease caused by mutations or rearrangements in the
DNA or epigenetic machinery of a patient. An emerging field in cancer treatment targets key …

[HTML][HTML] Polyisoprenylated methylated protein methyl esterase as a putative drug target for androgen-insensitive prostate cancer

RA Poku, F Amissah, R Duverna, BJ Aguilar… - …, 2014 - ncbi.nlm.nih.gov
Prostate cancer (CaP) is the most frequently diagnosed cancer in US men, with an estimated
236,590 new cases and 29,720 deaths in 2013. There exists the need to identify biomarkers …