The nasal cavity is an attractive route for both local and systemic drug delivery and holds
great potential for access to the brain via the olfactory region, an area where the blood–brain …

Nanoparticle (NP)-based materials have breakthrough applications in many fields of life,
such as in engineering, communications and textiles industries; food and bioenvironmental …

Switching to low-global warming potential (GWP) propellants for pressurized metered dose
inhalers (pMDIs) is crucial in current inhalation product development, as it is crucial to …

There is currently no in vitro technique for assessing plume geometry of nasal sprays under
airflow conditions. However, a majority of FDA approved nasal products recommend that …

Adjuvant system 04 (AS04) is in injectable human vaccines. AS04 contains two known
adjuvants, 3-O-desacyl-4′-monophosphoryl lipid A (MPL) and insoluble aluminum salts …

Orally inhaled drug products (OIDPs) are an important group of medicines traditionally used
to treat pulmonary diseases. Over the past decade, this trend has broadened, increasing …

Although high-speed laser imaging is the current standard to characterize the plume angle
of suspension-based pressurized metered dose inhalers (pMDIs), this method is limited by …

Respiratory drug delivery has been under the spotlight of research for the past few decades,
mainly due to rapid increase of pulmonary diseases. This type of drug delivery offers the …

The attractiveness and enhanced applications of nanoparticles (NPs) stem from their
exceptional properties at the nanoscale size, ie, 1-1000 nm, they may exhibit nano-specific …

The ability of a pharmaceutical inhalation medicine to penetrate the airways once entrained
in the patient's inhalation flow is a function of the physics of particle motion, airflow …