[HTML][HTML] Recent advances in understanding and managing phantom limb pain

A Aternali, J Katz - F1000Research, 2019 - ncbi.nlm.nih.gov
Post-amputation phantom limb pain (PLP) is highly prevalent and very difficult to treat. The
high-prevalence, high-pain intensity levels, and decreased quality of life associated with …

Mechanoneural interfaces for bionic integration

T Shu, G Herrera-Arcos, CR Taylor… - Nature Reviews …, 2024 - nature.com
Our expanding expertise in peripheral nerve regeneration and soft tissue reconstruction is
enabling the development of novel innervated tissue constructs that can be combined with …

Targeted muscle reinnervation improves pain and ambulation outcomes in highly comorbid amputees

BL Chang, J Mondshine, CE Attinger… - Plastic and …, 2021 - journals.lww.com
Background: Approximately 200,000 people undergo a lower extremity amputation each
year. Following amputation, patients suffer from chronic pain, inability to ambulate, and high …

Technological advances in prosthesis design and rehabilitation following upper extremity limb loss

TJ Bates, JR Fergason, SN Pierrie - Current reviews in musculoskeletal …, 2020 - Springer
Abstract Purpose of Review The complexity of the human extremity, particularly the upper
extremity and the hand, allows us to interact with the world. Prosthetists have struggled to …

Biology and pathophysiology of symptomatic neuromas

CD Hwang, YAJ Hoftiezer, FV Raasveld… - Pain, 2024 - journals.lww.com
Neuromas are a substantial cause of morbidity and reduction in quality of life. This is not
only caused by a disruption in motor and sensory function from the underlying nerve injury …

Targeted muscle reinnervation for the management of pain in the setting of major limb amputation

BR Peters, SA Russo, JM West… - SAGE open …, 2020 - journals.sagepub.com
The life altering nature of major limb amputations may be further complicated by neuroma
formation in up to 60% of the estimated 2 million major limb amputees in the United States …

Targeted muscle reinnervation and regenerative peripheral nerve interfaces for pain prophylaxis and treatment: a systematic review

JT Mauch, DS Kao, JL Friedly, Y Liu - PM&R, 2023 - Wiley Online Library
Objective Nerve pain frequently develops following amputations and peripheral nerve
injuries. Two innovative surgical techniques, targeted muscle reinnervation (TMR) and …

Factors related to neuropathic pain following lower extremity amputation

J Lans, OQ Groot, MHJ Hazewinkel… - Plastic and …, 2022 - journals.lww.com
Background: Lower extremity amputations are common, and postoperative neuropathic pain
(phantom limb pain or symptomatic neuroma) is frequently reported. The use of active …

Targeted muscle reinnervation: outcomes in treating chronic pain secondary to extremity amputation and phantom limb syndrome

CT McNamara, ML Iorio - Journal of Reconstructive …, 2020 - thieme-connect.com
Background Secondary to vascular disease, oncological resection, or devastating trauma,
lower extremity amputations are performed globally at a yearly rate exceeding 1 million …

[HTML][HTML] Targeted muscle reinnervation at the time of major limb amputation in traumatic amputees: early experience of an effective treatment strategy to improve pain

TL Frantz, JS Everhart, JM West, TV Ly… - JBJS Open …, 2020 - journals.lww.com
Background: Orthopaedic trauma etiologies are a common cause for amputation. Targeted
muscle reinnervation (TMR) is a technique aimed at reducing or preventing pain and …