Endotoxin exposure in allergy and asthma: reconciling a paradox
AH Liu - Journal of Allergy and Clinical Immunology, 2002 - Elsevier
Well-established evidence links endotoxin exposure, especially in the workplace, to airways
disease. Endotoxin can increase disease severity by acting as a natural adjuvant to …
disease. Endotoxin can increase disease severity by acting as a natural adjuvant to …
The inflammatory response in humans after inhalation of bacterial endotoxin: a review
J Thorn - Inflammation Research, 2001 - Springer
There is increasing evidence that diseases caused by organic dusts are mainly of an
inflammatory nature. Among the many agents present in organic dusts, bacterial endotoxin …
inflammatory nature. Among the many agents present in organic dusts, bacterial endotoxin …
House dust endotoxin and wheeze in the first year of life
JH Park, DR Gold, DL Spiegelman… - American journal of …, 2001 - atsjournals.org
We examined endotoxin exposure and wheezing episodes during the first year of life in a
birth cohort of 499 infants with one or both parents having a history of asthma or allergy. We …
birth cohort of 499 infants with one or both parents having a history of asthma or allergy. We …
Dose-response relationship to inhaled endotoxin in normal subjects
O Michel, AM Nagy, M Schroeven… - American journal of …, 1997 - atsjournals.org
Exposure to endotoxin and to its purified derivative lipopolysaccharide (LPS) is related to
several occupational pulmonary diseases and to severe domestic asthma. An inhalation of a …
several occupational pulmonary diseases and to severe domestic asthma. An inhalation of a …
Effect of inhaled interleukin-5 on airway hyperreactivity and eosinophilia in asthmatics
HZ Shi, CQ XIAO, D ZHONG, SM QIN, YI Liu… - American journal of …, 1998 - atsjournals.org
In order to investigate the role of interleukin-5 (IL-5) in airway hyperreactivity and
eosinophilia, we observed the effect of inhaled recombinant human IL-5 on airway …
eosinophilia, we observed the effect of inhaled recombinant human IL-5 on airway …
Total and respirable airborne dust endotoxin concentrations in three equine management systems
BC McGorum, J Ellison, RT Cullen - Equine veterinary journal, 1998 - Wiley Online Library
The concentrations of total and respirable airborne endotoxin in the breathing zone of a
pony in 3 different management systems, on 8 occasions, are reported. Airborne endotoxin …
pony in 3 different management systems, on 8 occasions, are reported. Airborne endotoxin …
Does environmental endotoxin exposure prevent asthma?
J Douwes, N Pearce, D Heederik - Thorax, 2002 - thorax.bmj.com
The evidence as to whether exposure to environmental airborne endotoxin plays a
protective or an inducing role in the development of asthma is reviewed. Studies of …
protective or an inducing role in the development of asthma is reviewed. Studies of …
Systemic responsiveness to lipopolysaccharide and polymorphisms in the toll-like receptor 4 gene in human beings
BACKGROUND: The response to lipopolysaccharide exposure is highly variable and might
be a result of genetic diversity between individuals. The toll-like receptor 4 (TLR-4) is the …
be a result of genetic diversity between individuals. The toll-like receptor 4 (TLR-4) is the …
Evaluation of the CD14/-260 polymorphism and house dust endotoxin exposure in the Barbados Asthma Genetics Study
A Zambelli-Weiner, E Ehrlich, ML Stockton… - Journal of allergy and …, 2005 - Elsevier
BACKGROUND: Both a functional promoter polymorphism in the gene encoding CD14 (C-
260T) and exposure to endotoxin are believed to play key roles in modulating the immune …
260T) and exposure to endotoxin are believed to play key roles in modulating the immune …
Pulmonary and systemic effects of inhaled endotoxin in control and heaves horses
RS Pirie, PM Dixon, DDS Collie… - Equine veterinary …, 2001 - Wiley Online Library
To investigate whether inhaled endotoxin contributes to airway inflammation and
dysfunction in stabled horses, control (n= 6) and asymptomatic heaves (previously termed …
dysfunction in stabled horses, control (n= 6) and asymptomatic heaves (previously termed …