Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Health benefits of exercise

GN Ruegsegger, FW Booth - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Overwhelming evidence exists that lifelong exercise is associated with a longer health span,
delaying the onset of 40 chronic conditions/diseases. What is beginning to be learned is the …

Regulatory T cells shield muscle mitochondria from interferon-γ–mediated damage to promote the beneficial effects of exercise

PK Langston, Y Sun, BA Ryback, AL Mueller… - Science …, 2023 - science.org
Exercise enhances physical performance and reduces the risk of many disorders such as
cardiovascular disease, type 2 diabetes, dementia, and cancer. Exercise characteristically …

Genetics and sports performance: the present and future in the identification of talent for sports based on DNA testing

D Varillas-Delgado, J Del Coso… - European journal of …, 2022 - Springer
The impact of genetics on physiology and sports performance is one of the most debated
research aspects in sports sciences. Nearly 200 genetic polymorphisms have been found to …

Adaptations to endurance and strength training

DC Hughes, S Ellefsen, K Baar - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
The capacity for human exercise performance can be enhanced with prolonged exercise
training, whether it is endurance-or strength-based. The ability to adapt through exercise …

Regulation of increased blood flow (hyperemia) to muscles during exercise: a hierarchy of competing physiological needs

MJ Joyner, DP Casey - Physiological reviews, 2015 - journals.physiology.org
This review focuses on how blood flow to contracting skeletal muscles is regulated during
exercise in humans. The idea is that blood flow to the contracting muscles links oxygen in …

Molecular transducers of physical activity consortium (MoTrPAC): mapping the dynamic responses to exercise

JA Sanford, CD Nogiec, ME Lindholm, JN Adkins… - Cell, 2020 - cell.com
Exercise provides a robust physiological stimulus that evokes cross-talk among multiple
tissues that when repeated regularly (ie, training) improves physiological capacity, benefits …

[HTML][HTML] Exercise metabolism and the molecular regulation of skeletal muscle adaptation

B Egan, JR Zierath - Cell metabolism, 2013 - cell.com
Preservation of aerobic fitness and skeletal muscle strength through exercise training can
ameliorate metabolic dysfunction and prevent chronic disease. These benefits are mediated …

[HTML][HTML] Lack of exercise is a major cause of chronic diseases

FW Booth, CK Roberts, MJ Laye - Comprehensive physiology, 2012 - ncbi.nlm.nih.gov
Chronic diseases are major killers in the modern era. Physical inactivity is a primary cause
of most chronic diseases. The initial third of the article considers: activity and prevention …

The impact of prehabilitation on patient outcomes in hepatobiliary, colorectal, and upper gastrointestinal cancer surgery: a PRISMA-accordant meta-analysis

JE Lambert, LD Hayes, TJ Keegan, DA Subar… - Annals of …, 2021 - journals.lww.com
Objective: To determine the impact of prehabilitation on hospital length of stay, functional
capacity, complications, and mortality after surgery in patients with hepatobiliary, colorectal …