Research from over the past 20 years has implicated dipeptidyl peptidase (DPP) IV and its
family members in many processes and different pathologies of the immune system. Most …

Dipeptidyl-peptidase IV (DPP4), originally identified as an aminopeptidase in 1960s, is an
ubiquitously expressed protease presented as either a membrane-bound or soluble form …

Chemokines are pivotal players in instigation and perpetuation of synovitis through
leukocytes egress from the blood circulation into the inflamed articulation. Multitudinous …

Estrogen deficiency is the main factor underlying postmenopausal osteoporosis. A large
number of neuropeptides, which regulate skeletal metabolism, potentially represent a …

Neuropeptide Y (NPY), a major autonomic nervous system and stress mediator, is emerging
as an important regulator of inflammation, implicated in autoimmunity, asthma …

Vasoactive intestinal peptide (VIP) plays important roles in many biological functions, such
as, stimulation of contractility in the heart, vasodilation, promoting neuroendocrine-immune …

Neuropeptide Y (NPY) is known to regulate bone homeostasis; however, its functional role
as a risk factor during osteoarthritis (OA) remains elusive. In this study, we aim to investigate …

Abstract Dipeptidyl peptidase 4 (DPP-4) is a serine protease, which has enzymatic activity to
selectively clean the N-terminal dipeptide of peptides and proteins with proline or alanine in …

We studied dipeptidyl peptidase IV (DPP-IV, CD26) expression in different T helper cells and
serum soluble DPP-IV/sCD26 levels in rheumatoid arthritis (RA) patients, correlated these …

Fibromyalgia (FM) is a chronic pain syndrome with number of symptoms that present
challenge in terms of diagnosis and treatment. Patients with FM show abnormal profile of …