[HTML][HTML] Anticancer drugs: recent strategies to improve stability profile, pharmacokinetic and pharmacodynamic properties

G Ioele, M Chieffallo, MA Occhiuzzi, M De Luca… - Molecules, 2022 - mdpi.com
In past decades, anticancer research has led to remarkable results despite many of the
approved drugs still being characterized by high systemic toxicity mainly due to the lack of …

Potential enhancement and targeting strategies of polymeric and lipid-based nanocarriers in dermal drug delivery

E Kahraman, S Güngör, Y Özsoy - Therapeutic delivery, 2017 - Taylor & Francis
Nanocarriers used for alternative drug-delivery strategies have gained interest due to
improved penetration and delivery of drugs into specific regions of the skin in recent years …

[HTML][HTML] Ascorbic acid encapsulated into negatively charged liposomes exhibits increased skin permeation, retention and enhances collagen synthesis by fibroblasts

L Maione-Silva, EG de Castro, TL Nascimento… - Scientific reports, 2019 - nature.com
Ascorbic acid (AA) is widely used in cosmetic formulations due to its antioxidant property
and ability to increase collagen synthesis. Here, we encapsulated AA in vesicles with …

Chaulmoogra oil based methotrexate loaded topical nanoemulsion for the treatment of psoriasis

P Rajitha, P Shammika, S Aiswarya… - Journal of drug delivery …, 2019 - Elsevier
Chaulmoogra oil based methotrexate loaded nanoemulsion was prepared via emulsification
technique using tween 80 and ethanol as surfactants. The formulation was characterized by …

Sodium dodecyl sulfate improved stability and transdermal delivery of salidroside-encapsulated niosomes via effects on zeta potential

Y Zhang, Q Jing, H Hu, Z He, T Wu, T Guo… - International journal of …, 2020 - Elsevier
Niosomes are novel carriers that show superior transdermal permeation enhancement but
require the addition of charged stabilizers. In this study, niosomes were prepared using …

[HTML][HTML] Lornoxicam-loaded chitosan-decorated nanoemulsion: preparation and in vitro evaluation for enhanced transdermal delivery

RU Khan, SU Shah, SA Rashid, F Naseem, KU Shah… - Polymers, 2022 - mdpi.com
Nanoemulsions are promising drug delivery systems for the administration of poorly soluble
drugs like lornoxicam (LRX) by oral or parenteral routes. Such formulations work perfectly for …

[HTML][HTML] Phototoxic or photoprotective?—advances and limitations of titanium (IV) oxide in dermal formulations—a review

M Gackowski, T Osmałek, A Froelich, F Otto… - International Journal of …, 2023 - mdpi.com
The widespread role of titanium (IV) oxide (TiO2) in many industries makes this substance of
broad scientific interest. TiO2 can act as both a photoprotector and photocatalyst, and the …

Innovative topical niosomal gel formulation containing diclofenac sodium (niofenac)

J Akbari, M Saeedi, K Morteza-Semnani… - Journal of Drug …, 2022 - Taylor & Francis
The purpose of this research was to enhance the transdermal delivery of diclofenac sodium
niosomal formulations. To characterise the obtained niosomes, SEM, XRPD, DSC and ATR …

Topical Delivery of Fenoprofen Calcium via Elastic Nano-vesicular Spanlastics: Optimization Using Experimental Design and In Vivo Evaluation

DA Farghaly, AA Aboelwafa, MY Hamza… - AAPS PharmSciTech, 2017 - Springer
The aim of this study was to investigate the potential of surfactant-based nanovesicular
system (spanlastics) for topical delivery of fenoprofen calcium (FPCa) to eliminate its oral …

Comparative anti-psoriatic efficacy studies of clobetasol loaded chitin nanogel and marketed cream

R Panonnummal, R Jayakumar, M Sabitha - European journal of …, 2017 - Elsevier
In the present study chitin nanogel loaded with anti-psoriatic drug clobetasol was developed
(CLCNG) for its topical delivery in psoriasis. CLCNG had the particle size of 132±14 nm, with …