Direct compaction (DC) is the preferred choice for tablet manufacturing; however, only less
than 20% of active pharmaceutical ingredients could be compacted via DC as its high …

Whilst monotherapy is traditionally the preferred treatment starting point for chronic
conditions such as hypertension and diabetes, other diseases require the use of multiple …

Hyperlipidemia is still the leading cause of heart disease in patients with hypertension. The
purpose of this study is to make rosuvastatin calcium (ROS) and atenolol (AT) bilayer tablets …

In the present study, specific energy for grinding and physical properties of wheat, canola,
oat and barley straw grinds were investigated. The initial moisture content of the straw was …

The pharmaceutical tablet formulation design is a risky and challenging process since it
largely depends on experience. The fundamental reasons lie in the lack of understanding of …

The objective of this study was to investigate the effect of large granulated lactose carrier
particle systems on aerosol performance of dry powder inhaler formulations. Granulated …

This study aimed to develop novel co-processed tablet fillers based on the principle of
particle engineering for direct compaction and to compare the characteristics of co …

Abstract The SeDeM Expert Diagram System is a galenic pre-formulation system, which
evaluates the suitability of excipients and active pharmaceutical ingredients (API's) for direct …

Grinding aids are organic compounds that chemically attach to a sufficient amount of particle
surfaces and prevent the formation of gravitational forces between particles. With the use of …

Hydrophilic nanofibers offer promising potential for the delivery of drugs with diverse
characteristics. Yet, the effects of different drugs incorporated into these nanofibers on their …