Direct compaction: An update of materials, trouble-shooting, and application
Z Li, LJ Zhao, X Lin, L Shen, Y Feng - International Journal of …, 2017 - Elsevier
Direct compaction (DC) is the preferred choice for tablet manufacturing; however, only less
than 20% of active pharmaceutical ingredients could be compacted via DC as its high …
than 20% of active pharmaceutical ingredients could be compacted via DC as its high …
Fixed-dose combination formulations in solid oral drug therapy: Advantages, limitations, and design features
CA Wilkins, H Hamman, JH Hamman, JH Steenekamp - Pharmaceutics, 2024 - mdpi.com
Whilst monotherapy is traditionally the preferred treatment starting point for chronic
conditions such as hypertension and diabetes, other diseases require the use of multiple …
conditions such as hypertension and diabetes, other diseases require the use of multiple …
Tailoring of rosuvastatin calcium and atenolol bilayer tablets for the management of hyperlipidemia associated with hypertension: a preclinical study
Hyperlipidemia is still the leading cause of heart disease in patients with hypertension. The
purpose of this study is to make rosuvastatin calcium (ROS) and atenolol (AT) bilayer tablets …
purpose of this study is to make rosuvastatin calcium (ROS) and atenolol (AT) bilayer tablets …
Grinding energy and physical properties of chopped and hammer-milled barley, wheat, oat, and canola straws
In the present study, specific energy for grinding and physical properties of wheat, canola,
oat and barley straw grinds were investigated. The initial moisture content of the straw was …
oat and barley straw grinds were investigated. The initial moisture content of the straw was …
SeDeM expert system for directly compressed tablet formulation: A review and new perspectives
S Dai, B Xu, G Shi, J Liu, Z Zhang, X Shi, Y Qiao - Powder Technology, 2019 - Elsevier
The pharmaceutical tablet formulation design is a risky and challenging process since it
largely depends on experience. The fundamental reasons lie in the lack of understanding of …
largely depends on experience. The fundamental reasons lie in the lack of understanding of …
[HTML][HTML] Evaluation of granulated lactose as a carrier for DPI formulations 1: effect of granule size
The objective of this study was to investigate the effect of large granulated lactose carrier
particle systems on aerosol performance of dry powder inhaler formulations. Granulated …
particle systems on aerosol performance of dry powder inhaler formulations. Granulated …
Differences in fundamental and functional properties of HPMC co-processed fillers prepared by fluid-bed coating and spray drying
QQ Dong, MM Zhou, X Lin, L Shen, Y Feng - European Journal of …, 2018 - Elsevier
This study aimed to develop novel co-processed tablet fillers based on the principle of
particle engineering for direct compaction and to compare the characteristics of co …
particle engineering for direct compaction and to compare the characteristics of co …
The SeDeM Expert Diagram System: Its performance and predictability in direct compressible formulations containing novel excipients and different types of active …
JC Scholtz, JH Steenekamp, JH Hamman, LR Tiedt - Powder technology, 2017 - Elsevier
Abstract The SeDeM Expert Diagram System is a galenic pre-formulation system, which
evaluates the suitability of excipients and active pharmaceutical ingredients (API's) for direct …
evaluates the suitability of excipients and active pharmaceutical ingredients (API's) for direct …
Effective role of grinding aids in the dry grinding performance of calcite
D Katircioglu-Bayel - Powder Technology, 2023 - Elsevier
Grinding aids are organic compounds that chemically attach to a sufficient amount of particle
surfaces and prevent the formation of gravitational forces between particles. With the use of …
surfaces and prevent the formation of gravitational forces between particles. With the use of …
The Incorporated Drug Affects the Properties of Hydrophilic Nanofibers
Č Dragar, R Roškar, P Kocbek - Nanomaterials, 2024 - mdpi.com
Hydrophilic nanofibers offer promising potential for the delivery of drugs with diverse
characteristics. Yet, the effects of different drugs incorporated into these nanofibers on their …
characteristics. Yet, the effects of different drugs incorporated into these nanofibers on their …