Multiple pathways for pathological calcification in the human body

N Vidavsky, JAMR Kunitake… - Advanced healthcare …, 2021 - Wiley Online Library
Biomineralization of skeletal components (eg, bone and teeth) is generally accepted to
occur under strict cellular regulation, leading to mineral–organic composites with …

Introduction to infrared and Raman-based biomedical molecular imaging and comparison with other modalities

CFGC Geraldes - Molecules, 2020 - mdpi.com
Molecular imaging has rapidly developed to answer the need of image contrast in medical
diagnostic imaging to go beyond morphological information to include functional differences …

Biomineralogical signatures of breast microcalcifications

JAMR Kunitake, D Sudilovsky, LM Johnson, HC Loh… - Science …, 2023 - science.org
Microcalcifications, primarily biogenic apatite, occur in cancerous and benign breast
pathologies and are key mammographic indicators. Outside the clinic, numerous …

Raman spectroscopy reveals that biochemical composition of breast microcalcifications correlates with histopathologic features

R Vanna, C Morasso, B Marcinnò, F Piccotti, E Torti… - Cancer research, 2020 - AACR
Breast microcalcifications are a common mammographic finding. Microcalcifications are
considered suspicious signs of breast cancer and a breast biopsy is required, however …

Measuring and modelling tumour heterogeneity across scales

GF Beeghly, AA Shimpi, RN Riter… - Nature Reviews …, 2023 - nature.com
Cancer development, progression and therapy response are heterogeneous and patient-
specific. The biological and physical properties of tumour cells and their surrounding tissue …

[HTML][HTML] Quantitative chemical imaging of breast calcifications in association with neoplastic processes

KS Shin, M Laohajaratsang, S Men, B Figueroa… - Theranostics, 2020 - ncbi.nlm.nih.gov
Calcifications play an essential role in early breast cancer detection and diagnosis.
However, information regarding the chemical composition of calcifications identified on …

[HTML][HTML] Magnesium whitlockite–omnipresent in pathological mineralisation of soft tissues but not a significant inorganic constituent of bone

FA Shah - Acta Biomaterialia, 2021 - Elsevier
Whitlockite is a calcium phosphate that was first identified in minerals collected from the
Palermo Quarry, New Hampshire. The terms magnesium whitlockite [Mg-whitlockite; Ca 18 …

Pathological mineralization: the potential of mineralomics

E Tsolaki, S Bertazzo - Materials, 2019 - mdpi.com
Pathological mineralization has been reported countless times in the literature and is a well-
known phenomenon in the medical field for its connections to a wide range of diseases …

[PDF][PDF] Scanning electron microscopy—a powerful imaging technique for the clinician

D Bazin, E Bouderlique… - Comptes …, 2022 - comptes-rendus.academie-sciences …
Résumé Since its first use several decades ago, scanning electron microscopy has been
used in numerous investigations dedicated to biological systems. This contribution focuses …

Exploration of utility of combined optical photothermal infrared and Raman imaging for investigating the chemical composition of microcalcifications in breast cancer

P Bouzy, ID Lyburn, SE Pinder, R Scott… - Analytical …, 2023 - pubs.rsc.org
Microcalcifications play an important role in cancer detection. They are evaluated by their
radiological and histological characteristics but it is challenging to find a link between their …