Induced pluripotent stem (iPS) cells can be established via forced epigenetic
reprogramming of various somatic cells and selection based on given criteria. Human iPS …

Objective: The present study aimed to establish an induced pluripotent stem cell (iPSC) line
from acute myelogenous leukemia (AML) cells in vitro and identify their biological …

Human embryonic stem cells (hESCs) are pluripotent cells that have the potential to
differentiate into the three germ layers and possibly all tissues of the human body. To fulfil …

Background Targeted differentiation of stem cells is mainly achieved by the sequential
administration of defined growth factors and cytokines, although these approaches are quite …

We have generated a human feeder cell line from early second trimester Placental Stromal
Fibroblasts (ihPSF) stably over-expressing the polycomb protein BMI-1. These feeder cells …

Human embryonic stem cells (hESCs) are usually maintained in an undifferentiated state by
co-culture with feeder cells. The feeder cells are important for the growth of hESCs. A novel …

Heart failure is a common, disabling, and deadly disease affecting over 23 million people
worldwide. The prevalence of this disease continues to increase each year despite …

Pluripotent stem cells are considered a very promising source of cells for drug discovery and
regenerative medicine. Cardiomyocytes (CMs) are the most frequent type of differentiated …

Human ESC research raises ethical and political controversies. The reprogramming of
already differentiated somatic cells to generate iPS cells avoids the ethical problems specific …