This review article gives a high-level overview of the approaches across different scales of
organization and levels of abstraction. The studies covered in this paper include …

Brian 2 allows scientists to simply and efficiently simulate spiking neural network models.
These models can feature novel dynamical equations, their interactions with the …

Elucidating the intricate neural mechanisms underlying brain functions requires integrative
brain dynamics modeling. To facilitate this process, it is crucial to develop a general-purpose …

The need for reproducible, credible, multiscale biological modeling has led to the
development of standardized simulation platforms, such as the widely-used NEURON …

Simulations are an important tool for investigating brain function but large models are
needed to faithfully reproduce the statistics and dynamics of brain activity. Simulating large …

The NEURON simulator has been developed over the past three decades and is widely
used by neuroscientists to model the electrical activity of neuronal networks. Large network …

Abstract “Brian” is a popular Python-based simulator for spiking neural networks, commonly
used in computational neuroscience. GeNN is a C++-based meta-compiler for accelerating …

The principled design and discovery of biologically-and physically-informed models of
neuronal dynamics has been advancing since the mid-twentieth century. Recent …

OpenSBLI is an open-source code-generation system for compressible fluid dynamics
(CFD) on heterogeneous computing architectures. Written in Python, OpenSBLI is an explicit …

SpiNNaker is a massively parallel distributed architecture primarily focused on real time
simulation of spiking neural networks. The largest realization of the architecture consists of …