The advantages and challenges of using endolysins in a clinical setting
Antibiotic-resistant pathogens are increasingly more prevalent and problematic. Traditional
antibiotics are no longer a viable option for dealing with these multidrug-resistant microbes …
antibiotics are no longer a viable option for dealing with these multidrug-resistant microbes …
Endolysin, a promising solution against antimicrobial resistance
Antimicrobial resistance (AMR) is a global crisis for human public health which threatens the
effective prevention and control of ever-increasing infectious diseases. The advent of …
effective prevention and control of ever-increasing infectious diseases. The advent of …
Learning from bacteriophages-advantages and limitations of phage and phage-encoded protein applications
Z Drulis-Kawa, G Majkowska-Skrobek… - Current Protein and …, 2012 - ingentaconnect.com
The emergence of bacteria resistance to most of the currently available antibiotics has
become a critical therapeutic problem. The bacteria causing both hospital and community …
become a critical therapeutic problem. The bacteria causing both hospital and community …
Bacteriophage endolysins: applications for food safety
M Schmelcher, MJ Loessner - Current opinion in biotechnology, 2016 - Elsevier
Highlights•Endolysins are promising agents for detection and control of foodborne
pathogens.•Cell wall binding domains can be used for specific detection of bacteria in …
pathogens.•Cell wall binding domains can be used for specific detection of bacteria in …
Potential for bacteriophage endolysins to supplement or replace antibiotics in food production and clinical care
There is growing concern about the emergence of bacterial strains showing resistance to all
classes of antibiotics commonly used in human medicine. Despite the broad range of …
classes of antibiotics commonly used in human medicine. Despite the broad range of …
Factors determining phage stability/activity: challenges in practical phage application
E Jończyk-Matysiak, N Łodej, D Kula… - Expert review of anti …, 2019 - Taylor & Francis
Introduction: Phages consist of nucleic acids and proteins that may lose their activity under
different physico-chemical conditions. The production process of phage formulations may …
different physico-chemical conditions. The production process of phage formulations may …
Effective removal of staphylococcal biofilms on various food contact surfaces by Staphylococcus aureus phage endolysin LysCSA13
Staphylococcal biofilms are recognized as a significant problem in the food industry
because of their high resistance to antibiotics, and the use of bacteriophages or endolysins …
because of their high resistance to antibiotics, and the use of bacteriophages or endolysins …
Bacteriophage-derived endolysins applied as potent biocontrol agents to enhance food safety
Y Chang - Microorganisms, 2020 - mdpi.com
Endolysins, bacteriophage-encoded enzymes, have emerged as antibacterial agents that
can be actively applied in food processing systems as food preservatives to control …
can be actively applied in food processing systems as food preservatives to control …
Lytic activity of the Vibrio cholerae type VI secretion toxin VgrG-3 is inhibited by the antitoxin TsaB
TM Brooks, D Unterweger, V Bachmann… - Journal of Biological …, 2013 - ASBMB
The type VI secretion system (T6SS) of Gram-negative bacteria has been implicated in
microbial competition; however, which components serve purely structural roles, and which …
microbial competition; however, which components serve purely structural roles, and which …
Phages and enzybiotics in food biopreservation
Presently, biopreservation through protective bacterial cultures and their antimicrobial
products or using antibacterial compounds derived from plants are proposed as feasible …
products or using antibacterial compounds derived from plants are proposed as feasible …