A comprehensive review of caged phosphines: synthesis, catalytic applications, and future perspectives
Phosphines have played an important role in the rapid rise of transition metal-catalysed
processes and with the possibility of fine-tuning the electronic and steric properties of these …
processes and with the possibility of fine-tuning the electronic and steric properties of these …
Discovery, synthesis, and scale-up of efficient palladium catalysts useful for the modification of nucleosides and heteroarenes
Nucleic acid derivatives are imperative biomolecules and are involved in life governing
processes. The chemical modification of nucleic acid is a fascinating area for researchers …
processes. The chemical modification of nucleic acid is a fascinating area for researchers …
Quadrol-Pd (ii) complexes: phosphine-free precatalysts for the room-temperature Suzuki–Miyaura synthesis of nucleoside analogues in aqueous media
JL Serrano, S Gaware, JA Pérez, J Pérez… - Dalton …, 2022 - pubs.rsc.org
Commercially available Quadrol, N, N, N′, N′-tetrakis (2-hydroxypropyl) ethylenediamine
(THPEN), has been used for the first time as a N^ N-donor neutral hydrophilic ligand in the …
(THPEN), has been used for the first time as a N^ N-donor neutral hydrophilic ligand in the …
Rapid plugged flow synthesis of nucleoside analogues via Suzuki-Miyaura coupling and heck Alkenylation of 5-Iodo-2'-deoxyuridine (or cytidine)
Nucleosides modification via conventional cross-coupling has been performed using
different catalytic systems and found to take place via long reaction times. However, since …
different catalytic systems and found to take place via long reaction times. However, since …
Scale-up of a Heck alkenylation reaction: Application to the synthesis of an amino-modifier nucleoside 'Ruth linker'
Ruth linker is a C5 pyrimidine modified nucleoside analogue widely utilized for the
incorporation of a primary amine in a synthetic oligonucleotide. The increasing demand for …
incorporation of a primary amine in a synthetic oligonucleotide. The increasing demand for …
PTABS: a unique water-soluble π-acceptor caged phosphine
R Sahu, AR Kapdi - Synlett, 2023 - thieme-connect.com
Caged phosphines have unique structures and provide many advantageous properties that
can be fine-tuned to develop efficient catalytic systems. Our research group recently …
can be fine-tuned to develop efficient catalytic systems. Our research group recently …
1, 3, 5‐Triaza‐7‐phosphaadamantane (PTA) Derived Caged Phosphines for Palladium‐Catalyzed Selective Functionalization of Nucleosides and Heteroarenes
SS Murthy Bandaru, S Bhilare, C Schulzke… - The Chemical …, 2021 - Wiley Online Library
Phosphines have, in combination with transition metals, played a pivotal role in the rapid
development of efficient catalytic processes. Caged phosphines constitute a class of three …
development of efficient catalytic processes. Caged phosphines constitute a class of three …
Water‐Soluble Pd‐Imidate Complexes as Versatile Catalysts for the Modification of Unprotected Halonucleosides
JL Serrano - The Chemical Record, 2022 - Wiley Online Library
Modification of unprotected nucleosides has been attracting continuous interest, since these
building blocks themselves and their phosphate‐upgraded corresponding nucleotides have …
building blocks themselves and their phosphate‐upgraded corresponding nucleotides have …
[HTML][HTML] Na2 [Pd (saccharinate) 4]: A new phosphine-free water-soluble catalyst with singular structure for modification of ribose nucleosides at room temperature
The easy synthesis of the anionic palladium catalyst containing saccharinate as only ligand
Na 2 [Pd (saccharinate) 4](I), starting from either Na 2 [PdCl 4] or Pd (AcO) 2, is reported …
Na 2 [Pd (saccharinate) 4](I), starting from either Na 2 [PdCl 4] or Pd (AcO) 2, is reported …
An expedient approach to pyrazolo [3, 4-b] pyridine-3-carboxamides via palladium-catalyzed aminocarbonylation
RM Alam, JJ Keating - Synthesis, 2021 - thieme-connect.com
Pyrazolo [3, 4-b] pyridine is a privileged scaffold found in many small drug molecules that
possess a wide range of pharmacological properties. Efforts to further develop and exploit …
possess a wide range of pharmacological properties. Efforts to further develop and exploit …