Kaposi sarcoma

E Cesarman, B Damania, SE Krown, J Martin… - Nature reviews Disease …, 2019 - nature.com
Kaposi sarcoma (KS) gained public attention as an AIDS-defining malignancy; its
appearance on the skin was a highly stigmatizing sign of HIV infection during the height of …

HIV-associated cancers and related diseases

R Yarchoan, TS Uldrick - New England Journal of Medicine, 2018 - Mass Medical Soc
AIDS-Associated Cancers Cancer is a leading cause of death in patients with AIDS. The
incidence of AIDS-defining cancers has been stable owing to highly active antiretroviral …

OF THE WORLD HEALTH ORGANIZATION CLASSIFICATION OF TUMORS OF THE HEMATOPOIETIC AND LYMPHOID TISSUES

JK Choi, W Xiao, X Chen, S Loghavi… - Modern Pathology, 2024 - Elsevier
This manuscript represents a review of lymphoblastic leukemia/lymphoma (acute
lymphoblastic leukemia/lymphoblastic lymphoma), acute leukemias of ambiguous lineage …

HIV-associated cancers and lymphoproliferative disorders caused by Kaposi sarcoma herpesvirus and Epstein-Barr virus

KA Lurain, R Ramaswami, LT Krug… - Clinical Microbiology …, 2024 - journals.asm.org
Within weeks of the first report of acquired immunodeficiency syndrome (AIDS) in 1981, it
was observed that these patients often had Kaposi sarcoma (KS), a hitherto rarely seen skin …

Viral infections

JC Sterling - Rook's Textbook of Dermatology, Ninth Edition, 2016 - Wiley Online Library
Skin disease due to viruses may be a primary infection of the epidermis or may arise
secondary to systemic infection. Depending on the virus, the effects may be necrotic damage …

Regulation and function of NF-κB transcription factors in the immune system

S Vallabhapurapu, M Karin - Annual review of immunology, 2009 - annualreviews.org
The mammalian Rel/NF-κB family of transcription factors, including RelA, c-Rel, RelB, NF-
κB1 (p50 and its precursor p105), and NF-κB2 (p52 and its precursor p100), plays a central …

Why do viruses cause cancer? Highlights of the first century of human tumour virology

PS Moore, Y Chang - Nature reviews cancer, 2010 - nature.com
The year 2011 marks the centenary of Francis Peyton Rous's landmark experiments on an
avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of …

Kaposi's sarcoma and its associated herpesvirus

EA Mesri, E Cesarman, C Boshoff - Nature Reviews Cancer, 2010 - nature.com
Kaposi's sarcoma (KS) is the most common cancer in HIV-infected untreated individuals.
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 …

The interplay between viral-derived miRNAs and host immunity during infection

R Mishra, A Kumar, H Ingle, H Kumar - Frontiers in immunology, 2020 - frontiersin.org
MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene
expression during cellular processes. The host-encoded miRNAs are known to modulate the …

Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses

Z Ma, SR Jacobs, JA West, C Stopford… - Proceedings of the …, 2015 - National Acad Sciences
Infection of cells with DNA viruses triggers innate immune responses mediated by DNA
sensors. cGMP-AMP synthase (cGAS) is a key DNA sensor that produces the cyclic …