Vaccines based on historical virus isolates provide limited protection from continuously
evolving RNA viruses, such as influenza viruses or coronaviruses, which occasionally spill …

SARS-CoV-2 infections manifest with a broad spectrum of presentations, ranging from
asymptomatic infections to severe pneumonia and fatal outcomes. This review centers on …

This ongoing, open-label, phase 2/3 trial compared the safety and immunogenicity of the
Omicron BA. 4/BA. 5-containing bivalent mRNA-1273.222 vaccine with the ancestral Wuhan …

Pre-existing SARS-CoV-2-reactive T cells have been identified in SARS-CoV-2-unexposed
individuals, potentially modulating COVID-19 and vaccination outcomes. Here, we provide …

Background The role of adaptive immune responses in long COVID remains poorly
understood, with contrasting hypotheses suggesting either an insufficient antiviral response …

Antibody-dependent enhancement (ADE) of infectious disease is a phenomenon whereby
host antibodies increase the severity of an infection. It is well established in viral infections …

Understanding the development of humoral immune responses of children and adolescents
to SARS-CoV-2 is essential for designing effective public health measures. Here we …

Coronavirus disease (Covid-19) has not only shaped awareness of the impact of infectious
diseases on global health. It has also provided instructive lessons for better prevention …

Despite many countries rapidly revising their strategies to prevent contagions, the number of
people infected with Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immune responses and
infection outcomes were evaluated in 2,686 patients with varying immune-suppressive …