Parallel artificial liquid membrane extraction coupled with UPLC-ESI-MS/MS method for high-throughput quantitation of repaglinide in diabetic patients
SA Ahmed, NA Abdallah, M Almaghrabi, YM Alahmadi - Talanta, 2024 - Elsevier
A high-throughput therapeutic monitoring method was developed for repaglinide (RPG) in
diabetic patients, combining parallel artificial liquid membrane extraction (PALME) with …
diabetic patients, combining parallel artificial liquid membrane extraction (PALME) with …
Validated kinetic spectrophotometric methods to optimize robustness study with youden factorial combinations to determine repaglinide using response surface …
SK Manirul Haque - Arabian Journal for Science and Engineering, 2023 - Springer
The response surface methodology combined Box–Behnken design was applied to
enhance the kinetic spectrophotometric methods to determine repaglinide in pharmaceutical …
enhance the kinetic spectrophotometric methods to determine repaglinide in pharmaceutical …
A sensitive HPLC-FLD method for the quantification of alpelisib, a novel phosphatidylinositol 3-kinase inhibitor, in rat plasma: Drug metabolism and pharmacokinetic …
Alpelisib, a novel phosphatidylinositol 3-kinase inhibitor, is an oral anticancer agent
approved for the treatment of advanced or metastatic breast cancer. In this study, a sensitive …
approved for the treatment of advanced or metastatic breast cancer. In this study, a sensitive …
Assessment of metabolic interaction between repaglinide and quercetin via mixed inhibition in the liver: In vitro and in vivo
Repaglinide (RPG), a rapid-acting meglitinide analog, is an oral hypoglycemic agent for
patients with type 2 diabetes mellitus. Quercetin (QCT) is a well-known antioxidant and …
patients with type 2 diabetes mellitus. Quercetin (QCT) is a well-known antioxidant and …
A simple and sensitive HPLC-FL method for bioanalysis of velpatasvir, a novel hepatitis C virus NS5A inhibitor, in rat plasma: Investigation of factors determining its …
Velpatasvir is a novel inhibitor of hepatitis C virus nonstructural protein 5A that received US
Food and Drug Administration approval for the treatment of patients with chronic hepatitis C …
Food and Drug Administration approval for the treatment of patients with chronic hepatitis C …
A sensitive HPLC-FL method to simultaneously determine febuxostat and diclofenac in rat plasma: assessment of metabolic drug interactions in vitro and in vivo
Febuxostat (FEB) is a selective xanthine oxidase (XO) inhibitor approved for chronic
management of hyperuricemia (HU) in patients with gout. Non-steroidal anti-inflammatory …
management of hyperuricemia (HU) in patients with gout. Non-steroidal anti-inflammatory …
[PDF][PDF] Development of new HPLC method for identification of metabolic degradation of N-pyrrolylhydrazide hydrazones with determined MAO-B activity in cellular …
A Mateeva, L Peikova, M Kondeva-Burdina… - …, 2022 - pharmacia.pensoft.net
In this research, a new rapid PR-HPLC method was developed for the determination of
metabolites in isolated rat hapatocytes. The chromatographic parameters, including the …
metabolites in isolated rat hapatocytes. The chromatographic parameters, including the …
Investigation of the factors responsible for the low oral bioavailability of alizarin using a sensitive LC‐MS/MS method: In vitro, in situ, and in vivo evaluations
Abstract Alizarin (1, 2‐dihydroxyanthraquinone) is an anthraquinone reddish dye widely
used for painting and textile dyeing. As the biological activity of alizarin has recently …
used for painting and textile dyeing. As the biological activity of alizarin has recently …
DoE-assisted HPLC method development and validation of enzalutamide and repaglinide in rat plasma
GN Reddy, A Jogvanshi, DS Reddy, L Chenkual… - Bioanalysis, 2024 - Taylor & Francis
Aim: A simple and rapid HPLC technique was developed and validated to simultaneously
estimate enzalutamide (ENZ) and repaglinide (REP) in rat plasma. Methods: In silico …
estimate enzalutamide (ENZ) and repaglinide (REP) in rat plasma. Methods: In silico …
Effect of Andrographis paniculata extract and Andrographolide on the pharmacokinetics of Aceclofenac and Celecoxib in rats
SJ More, SS Tandulwadkar, AR Balap… - Future Journal of …, 2023 - Springer
Abstract Background In India, for the treatment of cold, fever and inflammation, people
consume herbal remedies containing Andrographis paniculata Nees (APE) as main …
consume herbal remedies containing Andrographis paniculata Nees (APE) as main …