Current trends in the design of scaffolds for computer-aided tissue engineering

SM Giannitelli, D Accoto, M Trombetta, A Rainer - Acta biomaterialia, 2014 - Elsevier
Advances introduced by additive manufacturing have significantly improved the ability to
tailor scaffold architecture, enhancing the control over microstructural features. This has led …

A review on the use of computational methods to characterize, design, and optimize tissue engineering scaffolds, with a potential in 3D printing fabrication

S Zhang, S Vijayavenkataraman… - Journal of Biomedical …, 2019 - Wiley Online Library
The design and fabrication of tissue engineering scaffolds is a highly complex process. In
order to provide a proper architecture for cells to grow, proliferate, and differentiate to form …

In Vitro Three-Dimensional Bone Tissue Models: From Cells to Controlled and Dynamic Environment

G Bouët, D Marchat, M Cruel, L Malaval… - Tissue Engineering Part …, 2015 - liebertpub.com
Most of our knowledge of bone cell physiology is derived from experiments carried out in
vitro on polystyrene substrates. However, these traditional monolayer cell cultures do not …

[HTML][HTML] Modelling and simulation of the chondrocyte cell growth, glucose consumption and lactate production within a porous tissue scaffold inside a perfusion …

MS Hossain, DJ Bergstrom, XB Chen - Biotechnology Reports, 2015 - Elsevier
Mathematical and numerical modelling of the tissue culture process in a perfusion bioreactor
is able to provide insight into the fluid flow, nutrients and wastes transport, dynamics of the …

Modeling the flow and mass transport in a mechanically stimulated parametric porous scaffold under fluid-structure interaction approach

M Malvè, DJ Bergstrom, XB Chen - International Communications in Heat …, 2018 - Elsevier
Tissue engineering scaffolds combined with bioreactors are used to cultivate cells with the
aim of reproducing tissues and organs. The cultivating process is critical due to the delicate …

[HTML][HTML] Physical properties optimization of nerve guidance conduits utilizing genetic algorithm: A CFD analysis

K Nazarrashidi, A Rassoli, M Sharbatdar - Results in Engineering, 2024 - Elsevier
Nerve guidance conduits, or NGCs, used as structures in tissue engineering, play an
important role in reconstruction and the growth of axons after nerve injuries. To produce an …

Modeling the cellular microenvironment near a tissue-liquid interface during cell growth in a porous scaffold

DA Bratsun, I Krasnyakov - Interfacial Phenomena and Heat …, 2022 - dl.begellhouse.com
In recent years, tissue engineering has been developing rapidly, manifesting itself in the
emergence of applied studies within clinical practice and fundamental research devoted to …

Design and simulating lattice structures in the FE analysis of the femur bone

P Bazyar, E Sheidaee - Bioprinting, 2023 - Elsevier
Bone tissue engineering (BTE) research has reached a significant level of maturity. This
paper reviews the role of modeling and simulation in BTE, highlighting their exceptional …

[PDF][PDF] Computational fluid dynamics in 3D-printed scaffolds with different strand-orientation in perfusion bioreactors

AR Saatchi, H Seddiqi, G Amoabediny… - Iranian Journal of …, 2020 - ijcce.ac.ir
Bone tissue engineering strategies use fluid flow dynamics inside 3D-scaffolds in perfusion,
bioreactors mechanically stimulate cells in these scaffolds. Fluid flow dynamics depends on …

Prediction of cell growth rate over scaffold strands inside a perfusion bioreactor

MS Hossain, DJ Bergstrom, XB Chen - Biomechanics and modeling in …, 2015 - Springer
Mathematical and computational modeling of the dynamic process where tissue scaffolds
are cultured in perfusion bioreactors is able to provide insight into the cell and tissue growth …