Advances in biotechnological production of β-alanine

L Wang, Y Mao, Z Wang, H Ma, T Chen - World Journal of Microbiology …, 2021 - Springer
Abstract β-Alanine (3-aminopropionic acid) is the only naturally occurring β-type amino acid.
Although it is not incorporated into proteins, it has important physiological functions in the …

Biosynthesis of pantothenate

ME Webb, AG Smith, C Abell - Natural product reports, 2004 - pubs.rsc.org
Covering: 1933–2004Pantothenate is an essential metabolite for all biological systems,
however the biosynthetic pathway is limited to plants, eubacteria and archaea. This …

Biosynthesis of pantothenic acid and coenzyme A

R Leonardi, S Jackowski - EcoSal Plus, 2007 - Am Soc Microbiol
Pantothenate is vitamin B5 and is the key precursor for the biosynthesis of coenzyme A
(CoA), a universal and essential cofactor involved in a myriad of metabolic reactions …

Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin

B Macao, DGA Johansson, GC Hansson… - Nature structural & …, 2006 - nature.com
The single cell layer of the lungs and the gastrointestinal tract is protected by the mucus
formed by large glycoproteins called mucins. Transmembrane mucins typically contain 110 …

Elucidating biosynthetic pathways for vitamins and cofactors

ME Webb, A Marquet, RR Mendel, F Rébeillé… - Natural product …, 2007 - pubs.rsc.org
Covering: up to 2007 The elucidation of the pathways to the water-soluble vitamins and
cofactors has provided many biochemical and chemical challenges. This is a reflection both …

Photocatalytic CO2 Reduction Using CO2‐Binding Enzymes

H Terholsen, HD Huerta‐Zerón, C Möller… - Angewandte Chemie …, 2024 - Wiley Online Library
Novel concepts to utilize carbon dioxide are required to reach a circular carbon economy
and minimize environmental issues. To achieve these goals, photo‐, electro‐, thermal‐, and …

Structural insights into phosphatidylethanolamine formation in bacterial membrane biogenesis

G Cho, E Lee, J Kim - Scientific reports, 2021 - nature.com
Phosphatidylethanolamine (PE), a major component of the cellular membrane across all
domains of life, is synthesized exclusively by membrane-anchored phosphatidylserine …

Enhanced production of β-alanine through co-expressing two different subtypes of l-aspartate-α-decarboxylase

L Wang, X Piao, S Cui, M Hu… - Journal of Industrial …, 2020 - academic.oup.com
Abstract β-Alanine (β-Ala) is an important intermediate with numerous applications in food
and feed additives, pharmaceuticals, polymeric materials, and electroplating industries. Its …

GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production

E Mahootchi, S Cannon Homaei, R Kleppe, I Winge… - Science …, 2020 - science.org
Carnosine and related β-alanine–containing peptides are believed to be important
antioxidants, pH buffers, and neuromodulators. However, their biosynthetic routes and …

Synthesis and deployment of an elusive fluorovinyl cation equivalent: access to quaternary α-(1′-fluoro) vinyl amino acids as potential PLP enzyme inactivators

CD McCune, ML Beio, JM Sturdivant… - Journal of the …, 2017 - ACS Publications
Developing specific chemical functionalities to deploy in biological environments for
targeted enzyme inactivation lies at the heart of mechanism-based inhibitor development but …