Bipolar disorder is a recurrent chronic disorder characterised by fluctuations in mood state
and energy. It affects more than 1% of the world's population irrespective of nationality …

Bipolar disorder is a recurrent disorder that affects more than 1% of the world population and
usually has its onset during youth. Its chronic course is associated with high rates of …

Resting-state fMRI (rs-fMRI) has emerged as an alternative method to study brain function in
human and animal models. In humans, it has been widely used to study psychiatric …

Objectives Over the past two decades, there has been tremendous growth in research
regarding bipolar disorder (BD) among children and adolescents (ie, pediatric BD [PBD]) …

Objective: The authors sought to identify diagnostic risk factors of manic, mixed, or
hypomanic episodes in the offspring of parents with bipolar disorder (“high-risk offspring”) …

Objective: The authors sought to assess dimensional symptomatic predictors of new-onset
bipolar spectrum disorders in youths at familial risk of bipolar disorder (“at-risk” youths) …

OBJECTIVE: Depression and brief periods of (hypo) mania are linked to an increased risk of
progression to bipolar I or II disorder (BD) in children of bipolar parents. This randomized …

Importance Early identification of individuals at high risk for the onset of bipolar spectrum
disorder (BPSD) is key from both a clinical and research perspective. While previous work …

Objectives To clarify the clinical features preceding the onset of bipolar disorder (BD) has
become a public health priority for the prevention of high morbidity and mortality. BD …

Importance Behavioral high-risk phenotypes predict the onset of bipolar disorder among
youths who have parents with bipolar disorder. Few studies have examined whether early …