Peroxisome proliferator-activated receptors, farnesoid X receptor, and dual modulating drugs in hypertension

JD Imig - Frontiers in Physiology, 2023 - frontiersin.org
Hypertension characterized by an elevated blood pressure is a cardiovascular disease that
afflicts greater than one in every three adults worldwide. Nuclear receptors are large …

Farnesoid X receptor prevents neutrophil extracellular traps via reduced sphingosine-1-phosphate in chronic kidney disease

BA Jones, K Myakala, M Guha… - American Journal …, 2023 - journals.physiology.org
Farnesoid X receptor (FXR) activation reduces renal inflammation, but the underlying
mechanisms remain elusive. Neutrophil extracellular traps (NETs) are webs of DNA formed …

NAD+ activates renal metabolism and protects from chronic kidney disease in a model of Alport syndrome

BA Jones, DL Gisch, K Myakala, A Sadiq, YH Cheng… - bioRxiv, 2024 - biorxiv.org
Chronic kidney disease (CKD) is associated with renal metabolic disturbances, including
impaired fatty acid oxidation (FAO). Nicotinamide adenine dinucleotide (NAD+) is a small …

[PDF][PDF] Glomerulopatía relacionada a obesidad: Revisión a propósito de un caso

MS Nina, JP Soto, CT Barrientos - researchgate.net
La glomerulopatía relacionada a obesidad es una entidad clínica que no tiene más de 2
décadas de antigüedad, supone un desafío diagnóstico, por requerir de un estudio …