Atrial fibrillation: epidemiology, pathophysiology, and clinical outcomes

L Staerk, JA Sherer, D Ko, EJ Benjamin… - Circulation …, 2017 - Am Heart Assoc
The past 3 decades have been characterized by an exponential growth in knowledge and
advances in the clinical treatment of atrial fibrillation (AF). It is now known that AF genesis …

Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression

J Heijman, N Voigt, S Nattel, D Dobrev - Circulation research, 2014 - Am Heart Assoc
Atrial fibrillation (AF) is the most common clinically relevant arrhythmia and is associated
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …

Recent advances in the molecular pathophysiology of atrial fibrillation

R Wakili, N Voigt, S Kääb, D Dobrev… - The Journal of clinical …, 2011 - Am Soc Clin Investig
Atrial fibrillation (AF) is an extremely common cardiac rhythm disorder that causes
substantial morbidity and contributes to mortality. The mechanisms underlying AF are …

Animal models of atrial fibrillation

D Schüttler, A Bapat, S Kääb, K Lee, P Tomsits… - Circulation …, 2020 - Am Heart Assoc
Atrial fibrillation (AF) is the most common sustained arrhythmia encountered in humans and
is a significant source of morbidity and mortality. Despite its prevalence, our mechanistic …

[HTML][HTML] Structure and composition of pulmonary arteries, capillaries and veins

MI Townsley - Comprehensive Physiology, 2012 - ncbi.nlm.nih.gov
The pulmonary vasculature is comprised of three anatomic compartments connected in
series: the arterial tree, an extensive capillary bed, and the venular tree. Although in general …

Atrial Fibrillation: JACC Council Perspectives

MK Chung, M Refaat, WK Shen, V Kutyifa… - Journal of the American …, 2020 - jacc.org
Atrial fibrillation (AF) is an increasingly prevalent arrhythmia; its pathophysiology and
progression are well studied. Stroke and bleeding risk models have been created and …

Regulation of the pulmonary circulation in the fetus and newborn

Y Gao, JU Raj - Physiological reviews, 2010 - journals.physiology.org
During the development of the pulmonary vasculature in the fetus, many structural and
functional changes occur to prepare the lung for the transition to air breathing. The …

Development of the human heart

MFJ Buijtendijk, P Barnett… - American Journal of …, 2020 - Wiley Online Library
In 2014, an extensive review discussing the major steps of cardiac development focusing on
growth, formation of primary and chamber myocardium and the development of the cardiac …

Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop

EJ Benjamin, PS Chen, DE Bild, AM Mascette… - Circulation, 2009 - Am Heart Assoc
The National Heart, Lung, and Blood Institute convened an expert panel April 28 to 29,
2008, to identify gaps and recommend research strategies to prevent atrial fibrillation (AF) …

How to make a heart: the origin and regulation of cardiac progenitor cells

SD Vincent, ME Buckingham - Current topics in developmental biology, 2010 - Elsevier
The formation of the heart is a complex morphogenetic process that depends on the
spatiotemporally regulated contribution of cardiac progenitor cells. These mainly derive from …