Isoquinoline alkaloids, an important class of N‐based heterocyclic compounds, have
attracted considerable attention from researchers worldwide since the early 19th century …

Ethnopharmacological relevance Berberine is a quaternary ammonium isoquinoline
alkaloid, mainly extracted from plants berberaceae, papaveraceae, ranunculaceae and …

Background: Delayed wound healing is a diverse, multifactorial, complex and inter-related
complication of diabetes resulting in significant clinical morbidity. Hesperidin possesses …

Background Huntington's disease (HD) is a complex multifactorial neurodegenerative
disorder. Naringin, a flavanone glycoside exhibits potent anti-inflammatory and antiapoptotic …

Natural alkaloids are polycyclic, nitrogen-containing, and basic compounds obtained from
plants. In this review, the advances in bioactive alkaloids with respect to their chemical …

There is a vast pre-clinical literature suggesting that certain nutraceuticals have the potential
to aid the preservation of bone mass in the context of estrogen withdrawal, glucocorticoid …

Neonatal-streptozotocin (n-STZ)-induced diabetes mimics most of the clinicopathological
symptoms of type 2 diabetes mellitus (T2DM) peripheral neuropathy. Berberine, a plant …

Background Musculoskeletal disorders are a group of disorders that affect the joints, bones,
and muscles, causing long-term disability. Berberine, an isoquinoline alkaloid, has been …

Diabetic osteoporosis is a complication of diabetes mellitus, and can result in an increased
incidence of bone fractures and a delay in fracture healing. Berberine is one of the most …

Diabetes mellitus, especially type 2 diabetes mellitus (T2DM), has become a significant
public health burden. Rhizoma coptidis (RC), known as Huang Lian, is widely used for …