Diverse commensal populations are now regarded as key to physiological homeostasis and
protection against disease. Although bacteria are the most abundant component of …

Over the last few years, we have seen an increasing interest and demand for pigs in
biomedical research. Domestic pigs (Sus scrofa domesticus) are closely related to humans …

Entomopathogenic fungi are the only insect pathogens able to infect their host by adhesion
to the surface and penetration through the cuticle. Although the possibility of fungal infection …

Host defense peptides (HDPs) are primary components of the innate immune system with
diverse biological functions, such as antibacterial ability and immunomodulatory function …

Intestinal barrier function is achieved primarily through regulating the synthesis of mucins
and tight junction (TJ) proteins, which are critical for maintaining optimal gut health and …

Recent analysis of the bovine genome revealed an expanded suite of β-defensin genes that
encode what are referred to as antimicrobial or host defense peptides (HDPs). Whereas …

Experimental models of bacterial and viral infections in cattle have suggested vitamin D has
a role in innate immunity of cattle. The intracrine vitamin D pathway of bovine macrophages …

Background Disease resilience is the ability to maintain performance under pathogen
exposure but is difficult to select for because breeding populations are raised under high …

Traditionally, antibiotics are included in animal feed at subtherapeutic levels for growth
promotion and disease prevention. However, recent links between in-feed antibiotics and a …

Simple Summary This review explores the potential of human defensins, particularly HBD-1,
in combating colorectal cancer (CRC) initiation and progression. Highlighting the need for …