Although nearly all mammalian species are diploid, whole-genome duplications occur in
select mammalian tissues as part of normal development. Such programmed …

Bladder cancer is a significant health burden due to its high prevalence, risk of mortality,
morbidity, and high cost of medical care. Epidemiologic evidence suggests that diets rich in …

Background Fifty percent of patients with muscle–invasive bladder cancer (MI-BC) die from
their disease and current chemotherapy treatment only marginally increases survival. Novel …

The progression of urothelial bladder cancer (UC) is a complicated multi-step process. We
perform a comprehensive multi-omics analysis of 448 samples from 190 UC patients …

Bladder cancer is the sixth most common cancer in humans. This heterogeneous set of
lesions including urothelial carcinoma (Uca) and squamous cell carcinoma (SCC) arise from …

The Mitogen-Activated Protein Kinase (MAPK) network consists of tightly interconnected
signalling pathways involved in diverse cellular processes, such as cell cycle, survival …

The prognosis and treatment of bladder cancer have improved little in the past 20 years.
Bladder cancer remains a debilitating and often fatal disease, and is among the most costly …

Bladder cancer is one of the most financially burdensome cancers globally, from its
diagnostic to its terminal stages. The impact it imposes on patients and the medical …

Purpose: To identify a panel of epigenetic biomarkers for accurate bladder cancer (BlCa)
detection in urine sediments. Experimental Design: Gene expression microarray analysis of …

Bladder cancer is one of the most lethal cancers in the world. Despite the continuous
development of medical technologies and therapeutic strategies, the overall survival rate of …