Cationic lipids are one of the most widely used nonviral vectors for gene delivery and are
especially attractive because they can be easily synthesized and extensively characterized …

Abstract Initially, the Atherton–Todd (AT) reaction was applied for the synthesis of
phosphoramidates by reacting dialkyl phosphite with a primary amine in the presence of …

We report the preparation of mannosylated nanoparticles loaded with messenger RNA
(mRNA) that enhance the transfection of dendritic cells (DCs) in vivo and the anti-B16F10 …

Cationic lipids are the most common non-viral vectors used in gene delivery with a few
currently being investigated in clinical trials. However, like most other synthetic vectors …

Synthetic small interfering RNA (siRNA) has become the basis of a new generation of gene-
silencing cancer therapeutics. However, successful implementation of this novel therapy …

As a growing public health concern, the worldwide spread of antimicrobial resistance urges
the development of new therapies. Antibacterial photodynamic therapy (a‐PDT) may be an …

Self-assembled synthetic gene delivery systems represent the bottom-up approach to gene
delivery and gene silencing, in which scientists are designing novel cationic and procationic …

Complex diseases such as cancer and microbial infections are multifactorial in nature with
numerous redundant signalling pathways involved in the disease development.[1–3] …

The programmable endonuclease activity and simple usage of CRISPR/Cas9 have
revolutionized the field of genome editing. The binding of single guide RNA (sgRNA) by the …

The presented work describes the synthesis and characterization of a novel magnetic
cationic phospholipid (MCP) system with a stable dopamine anchor as well as its …