Making sense of astrocytic calcium signals—from acquisition to interpretation
A Semyanov, C Henneberger, A Agarwal - Nature Reviews …, 2020 - nature.com
Astrocytes functionally interact with neurons and with other brain cells. Although not
electrically excitable, astrocytes display a complex repertoire of intracellular Ca2+ signalling …
electrically excitable, astrocytes display a complex repertoire of intracellular Ca2+ signalling …
Calcium signaling in astrocytes and gliotransmitter release
Glia are as numerous in the brain as neurons and widely known to serve supportive roles
such as structural scaffolding, extracellular ionic and neurotransmitter homeostasis, and …
such as structural scaffolding, extracellular ionic and neurotransmitter homeostasis, and …
The ATP level in the medial prefrontal cortex regulates depressive-like behavior via the medial prefrontal cortex-lateral habenula pathway
S Lin, L Huang, Z Luo, X Li, S Jin, Z Du, D Wu… - Biological …, 2022 - Elsevier
Background Depression is the most common mental illness. Mounting evidence suggests
that dysregulation of extracellular ATP (adenosine triphosphate) is involved in the …
that dysregulation of extracellular ATP (adenosine triphosphate) is involved in the …
Aberrant calcium signals in reactive astrocytes: a key process in neurological disorders
E Shigetomi, K Saito, F Sano, S Koizumi - International journal of …, 2019 - mdpi.com
Astrocytes are abundant cells in the brain that regulate multiple aspects of neural tissue
homeostasis by providing structural and metabolic support to neurons, maintaining synaptic …
homeostasis by providing structural and metabolic support to neurons, maintaining synaptic …
Calcium signals in astrocyte microdomains, a decade of great advances
The glial cells astrocytes have long been recognized as important neuron-supporting
elements in brain development, homeostasis, and metabolism. After the discovery that the …
elements in brain development, homeostasis, and metabolism. After the discovery that the …
Rescue of astrocyte activity by the calcium sensor STIM1 restores long-term synaptic plasticity in female mice modelling Alzheimer's disease
A Lia, G Sansevero, A Chiavegato, M Sbrissa… - Nature …, 2023 - nature.com
Calcium dynamics in astrocytes represent a fundamental signal that through gliotransmitter
release regulates synaptic plasticity and behaviour. Here we present a longitudinal study in …
release regulates synaptic plasticity and behaviour. Here we present a longitudinal study in …
Two decades of astrocytes in neurovascular coupling
A Lia, A Di Spiezio, M Speggiorin… - Frontiers in Network …, 2023 - frontiersin.org
The brain is a highly energy demanding organ, which accounts in humans for the 20% of
total energy consumption at resting state although comprising only 2% of the body mass …
total energy consumption at resting state although comprising only 2% of the body mass …
Astrocytic calcium and cAMP in neurodegenerative diseases
M Sobolczyk, T Boczek - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
It is commonly accepted that the role of astrocytes exceeds far beyond neuronal scaffold and
energy supply. Their unique morphological and functional features have recently brough …
energy supply. Their unique morphological and functional features have recently brough …
Astrocytic IP3Rs: Beyond IP3R2
MW Sherwood, M Arizono, A Panatier… - Frontiers in cellular …, 2021 - frontiersin.org
Astrocytes are sensitive to ongoing neuronal/network activities and, accordingly, regulate
neuronal functions (synaptic transmission, synaptic plasticity, behavior, etc.) by the context …
neuronal functions (synaptic transmission, synaptic plasticity, behavior, etc.) by the context …
Simulation of calcium signaling in fine astrocytic processes: Effect of spatial properties on spontaneous activity
Astrocytes, a glial cell type of the central nervous system, have emerged as detectors and
regulators of neuronal information processing. Astrocyte excitability resides in transient …
regulators of neuronal information processing. Astrocyte excitability resides in transient …