Phosphorus‐substituted heterocycles represent an important class of organophosphorus
compounds, which not only widely exist in biologically active pharmaceuticals …

1. Introduction a-Aminophosphonic acids and their derivatives exhibit diverse biological
activities that are the basis of their important pharmacological applications. 1 Their …

Perimidines are versatile scaffolds and a fascinating class of N-heterocycles that have
evolved significantly in recent years due to their immense applications in life sciences …

The increasing importance of azaheterocyclic phosphonates in the agrochemical, synthetic,
and medicinal field has provoked an intense search in the development of synthetic routes …

A highly enantioselective addition of diphenyl phosphite to ketimines derived from isatins
has been achieved using a bifunctional organocatalyst, quinine-derived squaramide …

New and efficient multi-component methods have been developed for the synthesis of
spirooxindoles in the presence of a catalytic amount of p-TSA as an inexpensive and …

The enantioselective Michael addition of dialkyl phosphites to N-unprotected isatylidene
malononitriles has been established for the first time by using a simple bifunctional tertiary …

Aim: To obtain new hybrids derived from isatin and triazole. Materials & methods: A series of
oxindole–1-H-1, 2, 3-triazole hybrids (4a–l) were synthesized from 3-sulfenylated N …

New chiral tetrasubstituted aminophosphonic acid derivatives of hexahydroquinoxalin-2
(1H)-one were synthesised via highly diastereoselective hydrophosphonylation of the …

An efficient and simple method for the synthesis of new benzopyranopyrimidines via a
pseudo four-component reaction of salicylic aldehydes, malononitrile and various amines in …