The actions of many drugs involve enzyme inhibition. This is exemplified by the inhibitors of
monoamine oxidases (MAO) and the cholinsterases (ChE) that have been used for several …

In neurodegenerative disorders, including Parkinson's and Alzheimer's diseases, type B
monoamine oxidase (MAO-B) has been proposed to play a primary role though generating …

Prostate cancer (PCa) is a major cause of mortality and morbidity in men. Available
therapies yield limited outcome. We explored anti-PCa activity in a polyphenol-rich fraction …

Background There are reports of improved metabolic outcomes due to consumption of
germinated brown rice (GBR). Many of the functional effects of GBR can be linked to its high …

Monoamine oxidase (MAO) catalyzes the oxidative deamination of monoamines including
dopamine (DA). MAO expression is elevated in Parkinson's disease (PD). An increase in …

In Parkinson's disease, cell death of dopamine neurons in the substantia nigra progresses
and neuroprotective therapy is required to halt neuronal loss. In cellular and animal models …

Monoamine oxidases (MAOs) are mitochondrial enzymes which control the levels of
neurotransmitters in the brain and dietary amines in peripheral tissues via oxidative …

Historically, much of the focus on monoamine oxidases and their substrates has been in the
area of depression and the monoamine neurotransmitters serotonin (5-hydroxytryptamine) …

J. Neurochem.(2010) 114, 87–96. Abstract Pyridoxal 5′‐phosphate, the active form of
vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l‐amino acid …

Ketamine, a noncompetitive N-methyl-d-aspartic acid (NMDA) receptor antagonist is
commonly used as a pediatric anesthetic. We have previously shown that acetyl L-carnitine …