Since the beginning of pharmaceutical research, drug delivery methods have been an
integral part of it. Polymeric micelles (PMs) have emerged as multifunctional nanoparticles in …

Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Mutual interference between surface ligands on multifunctional nanoparticles remains a
significant obstacle to achieving optimal drug-delivery efficacy. Here, we develop ligand …

Polymeric micelles, self-assembling nano-constructs of amphiphilic copolymers with a core-
shell structure have been used as versatile carriers for delivery of drugs as well as nucleic …

Over the last decade, significant progress has been made in the field of drug delivery. The
advent of engineered nanoparticles has allowed us to circumvent the initial limitations to …

Various types of nanoparticles (NPs) have been used in delivering anticancer drugs to the
site of action. This area has become more attractive in recent years due to optimal size and …

Intrinsic anticancer drug resistance appearing prior to chemotherapy as well as acquired
resistance due to drug treatment, remain the dominant impediments towards curative cancer …

The chitosan-folate conjugate was synthesized initially and confirmed by FTIR and NMR
spectroscopic studies. Following, docetaxel (DXL) loaded non-targeted, single receptor and …

During the past two decades, the clinical use of biopharmaceutical products has markedly
increased because of their obvious advantages over conventional small-molecule drug …

Multicellular 3D cancer cell culture (spheroids) resemble to in vivo tumors in terms of shape,
cell morphology, growth kinetics, gene expression and drug response. However, these …