Local and systemic replicative fitness for viruses in specialist, generalist, and non-specialist interactions with salmonid hosts

DJ Páez, G Kurath, RL Powers… - Journal of General …, 2024 - microbiologyresearch.org
Host tissues represent diverse resources or barriers for pathogen replicative fitness. We
tested whether viruses in specialist, generalist, and non-specialist interactions replicate …

[HTML][HTML] Comparative susceptibilities of selected california chinook salmon and steelhead populations to isolates of L genogroup Infectious Hematopoietic Necrosis …

CM Bendorf, SC Yun, G Kurath, RP Hedrick - Animals, 2022 - mdpi.com
Simple Summary Chinook salmon in California conservation hatcheries have suffered
disease outbreaks and significant mortality due to the fish virus infectious hematopoietic …

[HTML][HTML] Virulence and infectivity of UC, MD, and L strains of infectious hematopoietic necrosis virus (IHNV) in four populations of Columbia River Basin Chinook …

DG Hernandez, W Brown, KA Naish, G Kurath - Viruses, 2021 - mdpi.com
Infectious Hematopoietic Necrosis Virus (IHNV) infects juvenile salmonid fish in
conservation hatcheries and aquaculture facilities, and in some cases, causes lethal …

Variation in within-host replication kinetics among virus genotypes provides evidence of specialist and generalist infection strategies across three salmonid host …

DJ Páez, D McKenney, MK Purcell, KA Naish… - Virus …, 2022 - academic.oup.com
Abstract Theory of the evolution of pathogen specialization suggests that a specialist
pathogen gains high fitness in one host, but this comes with fitness loss in other hosts. By …

Transmission routes maintaining a viral pathogen of steelhead trout within a complex multi‐host assemblage

R Breyta, I Brito, P Ferguson, G Kurath… - Ecology and …, 2017 - Wiley Online Library
This is the first comprehensive region wide, spatially explicit epidemiologic analysis of
surveillance data of the aquatic viral pathogen infectious hematopoietic necrosis virus …

[HTML][HTML] Shedding kinetics of Infectious Hematopoietic Necrosis Virus (IHNV) in juvenile spring-and fall-run Chinook salmon of the Columbia River Basin

DG Hernandez, G Kurath - Animals, 2022 - mdpi.com
Simple Summary When a virus infects a host it reproduces in that host and then sheds from
the host in order to find new hosts for more rounds of reproduction. Thus, virus shedding is a …

Coproduction and modeling spatial contact networks prevent bias about infectious hematopoietic necrosis virus transmission for Snake River Basin salmonids

JP Mattheiss, R Breyta, G Kurath, SL LaDeau… - Journal of …, 2023 - Elsevier
Much remains unknown about variation in pathogen transmission across the geographic
range of a free-ranging fish or animal species and about the influence of movement …

Infectious hematopoietic necrosis virus specialization in a multihost salmonid system

DJ Páez, SL LaDeau, R Breyta, G Kurath… - Evolutionary …, 2020 - Wiley Online Library
Many pathogens interact and evolve in communities where more than one host species is
present, yet our understanding of host–pathogen specialization is mostly informed by …

An epidemiological model of virus transmission in salmonid fishes of the Columbia River Basin

PFB Ferguson, R Breyta, I Brito, G Kurath… - Ecological Modelling, 2018 - Elsevier
We have developed a dynamic epidemiological model informed by records of viral presence
and genotypes to evaluate potential transmission routes maintaining a viral pathogen in …

[HTML][HTML] Genetics reveal long-distance virus transmission links in Pacific salmon

RB Breyta, WN Batts, G Kurath - Animals, 2022 - mdpi.com
Simple Summary The transmission of viruses between host populations is essential for
viruses to persist on the landscape. Therefore, the identification of specific transmission links …