[HTML][HTML] Myricetin: A review of the most recent research

X Song, L Tan, M Wang, C Ren, C Guo, B Yang… - Biomedicine & …, 2021 - Elsevier
Myricetin (MYR) is a flavonoid compound widely found in many natural plants including
bayberry. So far, MYR has been proven to have multiple biological functions and it is a …

The distinct roles of sialyltransferases in cancer biology and onco-immunology

M Hugonnet, P Singh, Q Haas… - Frontiers in …, 2021 - frontiersin.org
Aberrant glycosylation is a key feature of malignant transformation. Hypersialylation, the
enhanced expression of sialic acid-terminated glycoconjugates on the cell surface, has …

Engineered models to parse apart the metastatic cascade

LA Hapach, JA Mosier, W Wang… - NPJ precision …, 2019 - nature.com
While considerable progress has been made in studying genetic and cellular aspects of
metastasis with in vitro cell culture and in vivo animal models, the driving mechanisms of …

[HTML][HTML] Understanding patterns of brain metastasis in breast cancer and designing rational therapeutic strategies

EM Brosnan, CK Anders - Annals of translational medicine, 2018 - ncbi.nlm.nih.gov
One of the most feared sequelae after a diagnosis of advanced breast cancer is
development of metastases to the brain as this diagnosis can affect physical function …

Gangliosides: structures, biosynthesis, analysis, and roles in cancer

S Groux‐Degroote, Y Guérardel, P Delannoy - Chembiochem, 2017 - Wiley Online Library
Gangliosides are acidic glycosphingolipids containing one or more sialic acid residues.
They are essential compounds at the outer leaflet of the plasma membrane, where they …

Breast cancer brain metastasis: molecular mechanisms and directions for treatment

RMSM Pedrosa, DA Mustafa, R Soffietti… - Neuro …, 2018 - academic.oup.com
The development of brain metastasis (BM) of breast cancer is usually a late event with
deleterious effect on the prognosis. Treatment options for intracerebral seeding of breast …

Identification of hub genes to regulate breast cancer metastasis to brain by bioinformatics analyses

D Tang, X Zhao, LI Zhang, Z Wang… - Journal of Cellular …, 2019 - Wiley Online Library
Breast cancer with metastasis especially brain metastasis represents a significant cause of
morbidity and mortality in patients. In this study, we aimed to investigate the hub genes and …

microRNAs orchestrate pathophysiology of breast cancer brain metastasis: advances in therapy

RK Kanchan, JA Siddiqui, S Mahapatra, SK Batra… - Molecular cancer, 2020 - Springer
Brain metastasis (BM) predominantly occurs in triple-negative (TN) and epidermal growth
factor 2 (HER2)-positive breast cancer (BC) patients, and currently, there is an unmet need …

Identification and validation of a 3-gene methylation classifier for HPV-based cervical screening on self-samples

W Verlaat, BC Snoek, DAM Heideman, SM Wilting… - Clinical Cancer …, 2018 - AACR
Purpose: Offering self-sampling of cervico-vaginal material for high-risk human
papillomavirus (hrHPV) testing is an effective method to increase the coverage in cervical …

Melanoma-secreted amyloid beta suppresses neuroinflammation and promotes brain metastasis

K Kleffman, G Levinson, IVL Rose, LM Blumenberg… - Cancer discovery, 2022 - AACR
Brain metastasis is a significant cause of morbidity and mortality in multiple cancer types and
represents an unmet clinical need. The mechanisms that mediate metastatic cancer growth …