Big Potassium (BK) ion channels in biology, disease and possible targets for cancer immunotherapy

L Ge, NT Hoa, Z Wilson, G Arismendi-Morillo… - International …, 2014 - Elsevier
Abstract The Big Potassium (BK) ion channel is commonly known by a variety of names
(Maxi-K, KCNMA1, slo, stretch-activated potassium channel, KCa1. 1). Each name reflects a …

Mechanisms of intimate and long-distance cross-talk between glioma and myeloid cells: how to break a vicious cycle

T Wurdinger, K Deumelandt, HJ van der Vliet… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Glioma-associated microglia and macrophages (GAMs) and myeloid-derived suppressor
cells (MDSCs) condition the glioma microenvironment to generate an immunosuppressed …

[HTML][HTML] A composite network of conserved and tissue specific gene interactions reveals possible genetic interactions in glioma

A Voigt, K Nowick, E Almaas - PLoS computational biology, 2017 - journals.plos.org
Differential co-expression network analyses have recently become an important step in the
investigation of cellular differentiation and dysfunctional gene-regulation in cell and tissue …

[HTML][HTML] Fascin-1 knock-down of human glioma cells reduces their microvilli/filopodia while improving their susceptibility to lymphocyte-mediated cytotoxicity

NT Hoa, L Ge, KL Erickson, CA Kruse… - American journal of …, 2015 - ncbi.nlm.nih.gov
Cancer cells derived from Glioblastoma multiforme possess membranous protrusions
allowing these cells to infiltrate surrounding tissue, while resisting lymphocyte cytotoxicity …

[HTML][HTML] Small cell lung cancer cells express the late stage gBK tumor antigen: a possible immunotarget for the terminal disease

NT Hoa, L Ge, RB Tajhya, C Beeton… - American Journal of …, 2014 - ncbi.nlm.nih.gov
Big Potassium (BK) ion channels have several splice variants. One splice variant initially
described within human glioma cells is called the glioma BK channel (gBK). Using a gBK …

Temozolomide induces the expression of the glioma Big Potassium (gBK) ion channel, while inhibiting fascin-1 expression: possible targets for glioma therapy

NT Hoa, L Ge, F Martini, V Chau… - Expert Opinion on …, 2016 - Taylor & Francis
ABSTRACT Objective: Temozolomide (TMZ) improves Glioblastoma Multiforme (GBM)
patient survival. The invasive behavior of the glioma cells is the cause of GBM relapse. The …

[PDF][PDF] Advances in Bioscience and Clinical Medicine

SA Richard, NK Kortei, S Kampo - academia.edu
Hyaluronan (hyaluronic acid= HA) is ubiquitously present in the extracellular matrix (ECM) of
several mammalian tissues. HA is predominantly well secreted by the white matter of the …

The Pivotal Novel Pathogenic Roles of Hyaluronic Acid and its Receptors in Gliomas

SA Richard, NK Kortei, S Kampo - Advances in Bioscience and …, 2020 - journals.aiac.org.au
HA/CD44 as well as HA/RHAMM cross-talks resulted in glioma cell adhesion,
mechanosensing, as well as invasive motility. RHAMM was overexpressed in DIPG and may …