From the first measurements of the distribution of pulmonary blood flow using radioactive
tracers by West and colleagues (J Clin Invest 40: 1–12, 1961) allowing gravitational …

The pulmonary circulation is a low-pressure, low-resistance circuit whose primary function is
to deliver deoxygenated blood to, and oxygenated blood from, the pulmonary capillary bed …

Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

Recent experimental and imaging studies suggest that the influence of gravity on the
measured distribution of blood flow in the lung is largely through deformation of the …

Hypoxic pulmonary vasoconstriction (HPV) is thought to actively regulate ventilation-
perfusion (V̇a/Q̇) matching, reducing perfusion in regions of alveolar hypoxia. We …

Purpose To introduce a reproducible, nonenhanced 1H MRI method for rapid in vivo
functional assessment of the whole lung at 1.5 Tesla (T). Methods At different respiratory …

Objectives Congenital diaphragmatic hernia (CDH) leads to lung hypoplasia. Using dynamic
contrast-enhanced (DCE) MR imaging, lung perfusion can be quantified. As MR perfusion …

Long-term survival of lung transplant patients is limited, principally because of Bronchiolitis
Obliterans Syndrome (BOS). BOS is primarily classified based on airflow obstruction …

MRI images of pulmonary blood flow using arterial spin labeling (ASL) measure the delivery
of magnetically tagged blood to an image plane during one systolic ejection period …

Objective With a region of interest (ROI)-based approach 2-year-old children after congenital
diaphragmatic hernia (CDH) show reduced MR lung perfusion values on the ipsilateral side …