Treatment of cancer using anti-CD19 Chimeric Antigen Receptor
The invention provides compositions and methods for treating diseases associated with
expression of CD19, eg, by administering a recombinant T cell comprising the CD19 CAR as …
expression of CD19, eg, by administering a recombinant T cell comprising the CD19 CAR as …
Methods of making chimeric antigen receptor-expressing cells
2019-03-04 Assigned to NOVARTIS AG, THE TRUSTEES OF THE UNIVERSITY OF
PENNSYLVANIA reassignment NOVARTIS AG ASSIGNMENT OF ASSIGNORS INTEREST …
PENNSYLVANIA reassignment NOVARTIS AG ASSIGNMENT OF ASSIGNORS INTEREST …
Car-expressing cells against multiple tumor antigens and uses thereof
CH June, DJ Powell - US Patent 11,161,907, 2021 - Google Patents
The invention provides compositions and methods for treating cancer by using immune
effector cells (eg, T cells, NK cells) engineered to conditionally express an agent which …
effector cells (eg, T cells, NK cells) engineered to conditionally express an agent which …
Treatment of cancer using a CLL-1 chimeric antigen receptor
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
53761606&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
53761606&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Enhanced antigen presenting ability of RNA CAR T cells by co-introduction of costimulatory molecules
The invention provides T cells comprising nucleic acid sequence encoding a chimeric
antigen receptor and a nucleic acid sequence encoding an enhancer of T cell priming …
antigen receptor and a nucleic acid sequence encoding an enhancer of T cell priming …
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
G Beatty, B Engels, N Idamakanti, CH June… - US Patent …, 2020 - Google Patents
2019-09-09 Assigned to THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
reassignment THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA ASSIGNMENT …
reassignment THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA ASSIGNMENT …
Nucleic acid molecules encoding chimeric antigen receptors comprising a CD20 binding domain
B Brannetti, J Brogdon, B Engels, B Granda… - US Patent …, 2020 - Google Patents
2017-11-07 Assigned to NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC.
reassignment NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. ASSIGNMENT …
reassignment NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. ASSIGNMENT …
Human mesothelin chimeric antigen receptors and uses thereof
G Beatty, B Engels, N Idamakanti, CH June… - US Patent …, 2020 - Google Patents
Provided are compositions and methods for treating diseases associated with expression of
mesothelin. Also provided are a chimeric antigen receptor (CAR) specific to mesothelin …
mesothelin. Also provided are a chimeric antigen receptor (CAR) specific to mesothelin …
Methods for improving the efficacy and expansion of immune cells
F Bedoya, S Ghassemi, CH June… - US Patent …, 2020 - Google Patents
US10829735B2 - Methods for improving the efficacy and expansion of immune cells -
Google Patents US10829735B2 - Methods for improving the efficacy and expansion of …
Google Patents US10829735B2 - Methods for improving the efficacy and expansion of …
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
M Milone, E Wang - US Patent 10,640,553, 2020 - Google Patents
The present invention provides compositions and methods for regulating the specificity and
activity of T cells. In one embodiment, the invention provides a type of chimeric antigen …
activity of T cells. In one embodiment, the invention provides a type of chimeric antigen …