Tuberculosis (TB) which is caused by the resilient pathogen Mycobacterium tuberculosis
(MTB) has re-emerged to become a leading public health problem in the world. The growing …

The emergence of strains of Mycobacterium tuberculosis resistant to isoniazid (INH) has
underscored the need for the development of new anti-tuberculosis agents. INH is activated …

For over a decade, tuberculosis (TB) has been the leading cause of death among infectious
diseases. Since the 1950s, isoniazid has been used as a front-line drug in the treatment of …

Despite the resistance developed by the Mycobacterium tuberculosis (MTb) strains,
isoniazid (INH) has been recognized as one of the best drug for treatment of Tuberculosis …

Lysostaphin is an effective antimicrobial agent to Staphylococcus, especially for the
methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Staphylococcus …

The emergence of multidrug-resistant strains of Mycobacterium tuberculosis (MTB)
represents a major threat to global health. Isoniazid (INH) is a prodrug used in the first-line …

In this work, the antitubercular activity of a pentacyano (isoniazid) ferrate (II) compound (IQG-
607) was investigated using a macrophage model of Mycobacterium tuberculosis infection …

A pharmacophore design approach, based on the coordination chemistry of an intimate
molecular hybrid of active metabolites of pro-drugs, known to release active species upon …

We have previously demonstrated a potent in vitro inhibitory activity for two pentacyano
(isoniazid) ferrate (II) compounds, namely IQG-607 and IQG-639, against the Mycobacterium …

Tuberculosis has re-emerged as a worldwide threat, which has motivated the development
of new drugs. The antituberculosis complex Na 3 [Fe (CN) 5 (isoniazid)](IQG607) in …