Network medicine is an emerging area of research dealing with molecular and genetic
interactions, network biomarkers of disease, and therapeutic target discovery. Large-scale …

The SOX genes encode a family of more than 20 transcription factors that are critical
regulators of embryogenesis and developmental processes and, when aberrantly …

Simple Summary Triple negative breast cancer is a type of breast cancer that does not have
a selective and effective therapy. It is known that this cancer possesses high abundance of …

Breast cancers are divided into subtypes with different prognoses and treatment responses
based on global differences in gene expression. Luminal breast cancer gene expression …

Background Overcoming drug resistance is critical for increasing the survival rate of prostate
cancer (PCa). Docetaxel is the first cytotoxic chemotherapeutical approved for treatment of …

The transcription factor SOX10 plays an important role in vertebrate neural crest
development, including the establishment and maintenance of the melanocyte lineage …

Abstract Background Approximately 5–10% of HER2-positive breast cancers can be defined
by low expression of the Ste20-like kinase, SLK, and high expression of SOX10. Our lab has …

Lauren classification is a pathology-based gastric cancer (GC) subtyping system, which is
widely used in the clinical treatment of patients with GC. However, genome-scale molecular …

Impairing reconsolidation may disrupt drug memories to prevent relapse, meanwhile long-
term transcription regulations in the brain regions contribute to the occurrence of emotional …

Breast cancer is the second leading cause of death in women after lung cancer, and only
5% of patients with metastatic breast cancer survive beyond ten years of diagnosis …