MicroRNAs in placental health and disease

JF Mouillet, Y Ouyang, CB Coyne… - American journal of …, 2015 - Elsevier
MicroRNAs (miRNAs) constitute a large family of small noncoding RNAs that are encoded
by the genomes of most organisms. They regulate gene expression through …

Epigenetics, chromatin and genome organization: recent advances from the ENCODE project

L Siggens, K Ekwall - Journal of internal medicine, 2014 - Wiley Online Library
The organization of the genome into functional units, such as enhancers and active or
repressed promoters, is associated with distinct patterns of DNA and histone modifications …

Systematic identification and annotation of human methylation marks based on bisulfite sequencing methylomes reveals distinct roles of cell type-specific …

H Liu, X Liu, S Zhang, J Lv, S Li, S Shang… - Nucleic acids …, 2016 - academic.oup.com
DNA methylation is a key epigenetic mark that is critical for gene regulation in multicellular
eukaryotes. Although various human cell types may have the same genome, these cells …

[HTML][HTML] Kinetics of the chromosome 14 microRNA cluster ortholog and its potential role during placental development in the pregnant mare

P Dini, P Daels, SC Loux, A Esteller-Vico, M Carossino… - BMC genomics, 2018 - Springer
Background The human chromosome 14 microRNA cluster (C14MC) is a conserved
microRNA (miRNA) cluster across eutherian mammals, reported to play an important role in …

Differences in 5-HT2A and mGlu2 receptor expression levels and repressive epigenetic modifications at the 5-HT2A promoter region in the Roman low-(RLA-I) and …

L Fomsgaard, JL Moreno… - Molecular …, 2018 - Springer
Abstract The serotonin 2A (5-HT 2A) and metabotropic glutamate 2 (mGlu2) receptors
regulate each other and are associated with schizophrenia. The Roman high-(RHA-I) and …

MetaImprint: an information repository of mammalian imprinted genes

Y Wei, J Su, H Liu, J Lv, F Wang, H Yan… - …, 2014 - journals.biologists.com
Genomic imprinting is a complex genetic and epigenetic phenomenon that plays important
roles in mammalian development and diseases. Mammalian imprinted genes have been …

[HTML][HTML] DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression

C Cruceanu, E Kutsarova, ES Chen, DR Checknita… - BMC psychiatry, 2016 - Springer
Abstract Background The Synapsins (SYN1, SYN2, and SYN3) are important players in the
adult brain, given their involvement in synaptic transmission and plasticity, as well as in the …

DNA methylation dynamics: identification and functional annotation

H Liu, S Li, X Wang, J Zhu, Y Wei… - Briefings in …, 2016 - academic.oup.com
DNA methylation is an epigenetic modification of cytosines that undergoes dynamic
changes in a temporal, spatial and cell-type-specific manner. Recent advances in …

Identification of 4438 novel lincRNAs involved in mouse pre-implantation embryonic development

J Lv, H Liu, S Yu, H Liu, W Cui, Y Gao, T Zheng… - Molecular Genetics and …, 2015 - Springer
Long intergenic non-coding RNAs (lincRNAs) as a key group of non-coding RNAs have
gained substantial attention. Though lincRNAs have been systematically explored in various …

[HTML][HTML] Epigenetic heterogeneity of B-cell lymphoma: chromatin modifiers

L Hopp, L Nersisyan, H Löffler-Wirth, A Arakelyan… - Genes, 2015 - mdpi.com
We systematically studied the expression of more than fifty histone and DNA (de)
methylating enzymes in lymphoma and healthy controls. As a main result, we found that the …