This write-up provides a review on the development of validated stability-indicating assay
methods (SIAMs) for drug substances and products. The shortcomings of reported methods …

Pharmaceutical formulations have to fulfil various requirements with respect to their intended
use, either in the development phase or as a commercial product. New drug candidates with …

The solid-state chemistry of drugs has seen growing importance in the pharmaceutical
industry for the development of useful API (active pharmaceutical ingredients) of drugs and …

Photolytic transformation of aspartame–a widely used artificial sweetener–under the
simulated sunlight was studied for the first time. The experiments were conducted in pH …

Using pharmaceutical salts in solid dosage forms can raise stability concerns, especially salt
dissociation which can adversely affect the product performance. Therefore, a thorough …

Literature data relevant to the decision to allow a waiver of in vivo bioequivalence testing for
the marketing authorization of immediate-release, solid oral dosage forms containing …

In the present study, comprehensive stress testing of enalapril maleate was carried out
according to ICH guideline Q1A (R2). The drug was subjected to acid (0.1 N HCl), neutral …

The Process of New Drug Discovery and Development presents a practical methodology for
maximizing the ability of a multidisciplinary research team to discover and bring new drugs …

Background: The efficacy of the angiotensin-converting enzyme (ACE) inhibitor perindopril
in the treatment of hypertension, stable coronary artery disease, and heart failure is well …

We investigated the advantages of an external lubrication technique for tableting. A newly
developed external lubricating system was applied to tableting in a rotary tablet press using …