In recent decades, the biomedical applications of mesenchymal stem cells (MSCs) have
attracted increasing attention. MSCs are easily extracted from the bone marrow, fat, and …

Over the past ten years, the use of additive manufacturing techniques, also known as “3D
printing”, has steadily increased in a variety of scientific fields. There are a number of …

Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

Tissue engineering and regenerative medicine involve many different artificial and biologic
materials, frequently integrated in composite scaffolds, which can be repopulated with …

Biologic scaffolds composed of extracellular matrix (ECM) are widely used in both preclinical
animal studies and in many clinical applications to repair and reconstruct tissues. Recently …

Mammalian organs are challenging to study as they are fairly inaccessible to experimental
manipulation and optical observation. Recent advances in three-dimensional (3D) culture …

The pig is an omnivorous, monogastric species with many advantages to serve as an animal
model for human diseases. There are very high similarities to humans in anatomy and …

Approximately 100,000 individuals in the United States currently await kidney
transplantation, and 400,000 individuals live with end-stage kidney disease requiring …

Intestinal failure, following extensive anatomical or functional loss of small intestine, has
debilitating long-term consequences for children. The priority of patient care is to increase …

The field of regenerative medicine aims to replace tissues lost as a consequence of disease,
trauma or congenital abnormalities. Biomaterials serve as scaffolds for regenerative …