Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Conventional administration of drugs is limited by poor water solubility, low permeability,
and mediocre targeting. Safe and effective delivery of drugs and therapeutic agents remains …

New approaches in pharmaceutical chemistry have resulted in more complex drug
molecules in the quest to achieve higher affinity to their targets. However, these 'highly …

Wound healing and health care requirements have attracted more attention, and the need to
develop new drug-containing dressings to accelerate wound healing is required …

Micro-and nano-mesoporous silicate particles are considered potential drug delivery
systems because of their ordered pore structures, large surface areas and the ease with …

Silica-based ordered mesoporous materials have experienced impressive consideration in
drug delivery applications since they were first employed as drug delivery systems back in …

Mesoporous silica nanoparticles (MSNs) are arising as a promising delivery system for a
more effective and safer therapy of many diseases, such as cancer, osteoporosis and …

Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical
properties of the drug and its inter-relationship with the gastrointestinal tract. Drug solubility …

Mesoporous silica nanoparticles (MSNs) are widely used as a promising candidate for drug
delivery applications due to silica's favorable biocompatibility, thermal stability, and chemical …

Encapsulating poorly soluble drugs in mesoporous silicates is an emerging strategy to
improve drug dissolution. This study evaluates the applicability of the ordered mesoporous …