Kidney cancer is one of the 10 most common cancers in the United States with 90% being
attributed to renal cell carcinoma. Men, especially black men, are more likely to be affected …

Sarcomatoid dedifferentiation is an uncommon feature that can occur in most histological
subtypes of renal cell carcinomas (RCCs) and carries a decidedly poor prognosis …

PURPOSE To provide recommendations for the management of patients with metastatic
clear cell renal cell carcinoma (ccRCC). METHODS An Expert Panel conducted a systematic …

Background Nivolumab plus ipilimumab produced objective responses in patients with
advanced renal-cell carcinoma in a pilot study. This phase 3 trial compared nivolumab plus …

Background Stereotactic ablative body radiotherapy (SABR) is an option for oligometastatic
clear cell renal cell carcinoma (ccRCC) but is limited by a lack of prospective clinical trial …

Abstract Background An elevated Neutrophil-to-lymphocyte ratio (NLR) is associated with
worse outcomes in several malignancies. However, its role with contemporary immune …

Predicting novel microRNA (miRNA)-disease associations is clinically significant due to
miRNAs' potential roles of diagnostic biomarkers and therapeutic targets for various human …

Vascularization is fundamental to the growth and spread of tumor cells to distant sites. As a
consequence, angiogenesis, the sprouting of new blood vessels from existing ones, is a …

Over the past decade, our understanding of the biology and pathophysiology of renal cell
carcinoma (RCC) has improved significantly. Insight into the disease process has helped us …

Renal cancer represents 2% to 3% of all cancers, and its incidence is rising. The increased
use of ultrasonography and cross-sectional imaging has resulted in the clinical dilemma of …