Commercial nerve guidance conduits (NGCs) for repair of peripheral nerve discontinuities
are of little use in gaps larger than 30 mm, and for smaller gaps they often fail to compete …

Oceans have vast potential to develop high-value bioactive substances and biomaterials. In
the past decades, many biomaterials have come from marine organisms, but due to the wide …

Chitosan has various tissue regeneration effects. This study was designed to investigate the
nerve regeneration effect of Schwann cell (SC)-encapsulated chitosan-collagen hydrogel …

Nerve regeneration and repair still remain a huge challenge for both central nervous and
peripheral nervous system. Although some therapeutic substances, including …

Chitosan is a natural polymer derived from the deacetylation of chitin. It is mainly derived
from crustaceans and fungal sources. It has many intrinsic properties, such as …

The use of autografted nerve in surgical repair of peripheral nerve injuries (PNI) is severely
limited due to donor site morbidity and restricted tissue availability. As an alternative …

Peripheral nerve repair following injury is one of the most serious problems in neurosurgery.
Clinical outcomes are often unsatisfactory and associated with a huge socioeconomic …

Injuries to the peripheral nervous system are a common clinical issue, causing dysfunctions
of the motor and sensory systems. Surgical interventions such as nerve autografting are …

Low efficiency of nerve growth and unstable release of loaded drugs have become a major
problem in repairing peripheral nerve injury. Many intervention strategies were focused on …

The nervous system is a significant part of the human body, and peripheral nerve injury
caused by trauma can cause various functional disorders. When the broken end defect is …