The review of current knowledge on neutrophil gelatinase-associated lipocalin (NGAL)

K Romejko, M Markowska, S Niemczyk - International journal of molecular …, 2023 - mdpi.com
Neutrophil gelatinase-associated lipocalin (NGAL) is a 25-kDa protein that is secreted
mostly by immune cells such as neutrophils, macrophages, and dendritic cells. Its production …

Cardiorenal syndrome type 1: pathophysiological crosstalk leading to combined heart and kidney dysfunction in the setting of acutely decompensated heart failure

C Ronco, M Cicoira, PA McCullough - Journal of the American College of …, 2012 - jacc.org
Cardiorenal syndrome (CRS) type 1 is characterized as the development of acute kidney
injury (AKI) and dysfunction in the patient with acute cardiac illness, most commonly acute …

Novel biomarkers of heart failure

A Savic-Radojevic, M Pljesa-Ercegovac, M Matic… - Advances in clinical …, 2017 - Elsevier
Although substantial improvements have been made in majority of cardiac disorders, heart
failure (HF) remains a major health problem, with both increasing incidence and prevalence …

[HTML][HTML] Cardiac biomarkers: new tools for heart failure management

N Iqbal, B Wentworth, R Choudhary… - Cardiovascular …, 2012 - ncbi.nlm.nih.gov
The last decade has seen exciting advances in the field of biomarkers used in managing
patients with heart failure (HF). Biomarker research has broadened our knowledge base …

Pathogenesis of cardiorenal syndrome type 1 in acute decompensated heart failure: workgroup statements from the eleventh consensus conference of the Acute …

M Haase, C Müller, K Damman, PT Murray… - ADQI Consensus on …, 2013 - karger.com
Pathophysiological mechanisms of cardiorenal syndromes (CRS) types 1-5 are still sparsely
characterized. In an attempt to address this issue, a consensus conference on CRS was …

Cardiorenal syndrome

C Ronco, L Di Lullo - Heart failure clinics, 2014 - heartfailure.theclinics.com
The term cardiorenal syndrome (CRS) includes a broad spectrum of diseases within which
both the heart and kidneys are involved, acutely or chronically. According to a recent …

[HTML][HTML] Circulating extracellular vesicles in human cardiorenal syndrome promote renal injury in a kidney-on-chip system

E Chatterjee, RS Rodosthenous, V Kujala… - JCI insight, 2023 - ncbi.nlm.nih.gov
BACKGROUND Cardiorenal syndrome (CRS)—renal injury during heart failure (HF)—is
linked to high morbidity. Whether circulating extracellular vesicles (EVs) and their RNA …

Biomarkers in cardiorenal syndrome and potential insights into novel therapeutics

EYM Chung, K Trinh, J Li, SH Hahn… - Frontiers in …, 2022 - frontiersin.org
Heart and kidney failure often co-exist and confer high morbidity and mortality. The complex
bi-directional nature of heart and kidney dysfunction is referred to as cardiorenal syndrome …

Neutrophil gelatinase-associated lipocalin for acute kidney injury during acute heart failure hospitalizations: the AKINESIS study

AS Maisel, N Wettersten, DJ van Veldhuisen… - Journal of the American …, 2016 - jacc.org
Background: Worsening renal function (WRF) often occurs during acute heart failure (AHF)
and can portend adverse outcomes; therefore, early identification may help mitigate risk …

Urine IL-18, NGAL, IL-8 and serum IL-8 are biomarkers of acute kidney injury following liver transplantation

JC Sirota, A Walcher, S Faubel, A Jani, K McFann… - BMC nephrology, 2013 - Springer
Background AKI is common following liver transplantation and is associated with significant
morbidity and mortality. Biomarkers of AKI have not been well established in this setting but …