Second generation of antiepileptic drugs and oxidative stress

K Kośmider, M Kamieniak, SJ Czuczwar… - International Journal of …, 2023 - mdpi.com
Epilepsy is a chronic disease of the central nervous system characterized by recurrent
epileptic seizures. As a result of epileptic seizure or status epilepticus oxidants are …

Antiepileptic drugs in aquatic environments: Occurrence, toxicity, transformation mechanisms and fate

Q Liu, L Wang, X Xu, S Yan, J Zha… - Critical Reviews in …, 2023 - Taylor & Francis
The increasing consumption of antiepileptic drugs (AEDs) has led to their widespread
presence in aquatic environments, which poses a serious threat to human health and …

Characterization of N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD)-induced cardiotoxicity in larval zebrafish (Danio rerio)

C Fang, L Fang, S Di, Y Yu, X Wang, C Wang… - Science of The Total …, 2023 - Elsevier
Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is a type of p-
phenylenediamine (PPD), which is widely used in the manufacture of rubber tires owing to …

Identification, quantification, and prioritization of new emerging pollutants in domestic and industrial effluents, Korea: Application of LC-HRMS based suspect and non …

Y Choi, JH Lee, K Kim, H Mun, N Park, J Jeon - Journal of hazardous …, 2021 - Elsevier
The present study was designed to identify recently (or rarely) recognized or unreported
substances (RRS or URS) contained in the effluents from water treatment plants in two …

Ecotoxicological risk assessment of contaminants of emerging concern identified by “suspect screening” from urban wastewater treatment plant effluents at a territorial …

A Gosset, L Wiest, A Fildier, C Libert, B Giroud… - Science of the Total …, 2021 - Elsevier
Urban wastewater treatment plants (WWTP) are a major vector of highly ecotoxic
contaminants of emerging concern (CECs) for urban and sub-urban streams …

Comprehensive phenotyping and multi-omic profiling in the toxicity assessment of nanopolystyrene with different surface properties

HM Kim, NP Long, JE Min, NH Anh, SJ Kim… - Journal of Hazardous …, 2020 - Elsevier
There is a growing concern regarding the toxic effects of terrestrial nanoplastic
contaminants. However, an all-encompassing phenotyping-and omics-based strategy for the …

Molecular responses of daphnids to chronic exposures to pharmaceuticals

K O'Rourke, B Engelmann, R Altenburger… - International Journal of …, 2023 - mdpi.com
Pharmaceutical compounds are among several classes of contaminants of emerging
concern, such as pesticides, heavy metals and personal care products, all of which are a …

[HTML][HTML] The impact of pharmaceutical pollutants on daphnids–A metabolomic approach

K O'Rourke, C Virgiliou, G Theodoridis, H Gika… - Environmental …, 2023 - Elsevier
Pharmaceuticals have been classified as emerging contaminants in the aquatic ecosystem,
mainly due to their increased use and improper disposal. A significant range of …

Toxicity of gabapentin-lactam on the early developmental stage of zebrafish (Danio rerio)

Y He, D Jia, S Du, R Zhu, W Zhou, S Pan… - Environmental Pollution, 2021 - Elsevier
Abstract Gabapentin-lactam (GBP-L) is a transformation product (TP) of gabapentin (GBP), a
widely used anti-epileptic pharmaceutical. Due to its high persistence, GBP-L has been …

[HTML][HTML] Protective effects of 5-aminolevulinic acid against toxicity induced by alpha-cypermethrin to the liver-gut-microbiota axis in zebrafish

Y Cheng, J Zhang, F Gao, Y Xu, C Wang - … and Environmental Safety, 2022 - Elsevier
To explore whether and how 5-aminolevulinic acid (ALA) can relieve the toxicity to the liver-
gut-microbiota axis caused by alpha-cypermethrin (α-CP), adult zebrafish were exposed to α …