Toxicology of engineered nanomaterials: focus on biocompatibility, biodistribution and biodegradation

A Kunzmann, B Andersson, T Thurnherr, H Krug… - … et Biophysica Acta (BBA …, 2011 - Elsevier
BACKGROUND: It is widely believed that engineered nanomaterials will be increasingly
used in biomedical applications. However, before these novel materials can be safely …

Dendrimers in medicine: therapeutic concepts and pharmaceutical challenges

L Wu, M Ficker, JB Christensen… - Bioconjugate …, 2015 - ACS Publications
Dendrimers are three-dimensional macromolecular structures originating from a central core
molecule and surrounded by successive addition of branching layers (generation). These …

Rosmarinic acid exhibits anticancer effects via MARK4 inhibition

S Anwar, A Shamsi, M Shahbaaz, A Queen, P Khan… - Scientific Reports, 2020 - nature.com
Microtubule affinity regulating kinase (MARK4) is a potential drug target for different types of
cancer as it controls the early step of cell division. In this study, we have screened a series of …

Quercetin as a tyrosinase inhibitor: Inhibitory activity, conformational change and mechanism

M Fan, G Zhang, X Hu, X Xu, D Gong - Food Research International, 2017 - Elsevier
Quercetin, a flavonoid compound, was found to inhibit both monophenolase and
diphenolase activities of tyrosinase, and its inhibition against diphenolase activity was in a …

pH-dependent protein conformational changes in albumin: gold nanoparticle bioconjugates: a spectroscopic study

L Shang, Y Wang, J Jiang, S Dong - Langmuir, 2007 - ACS Publications
The conformational changes of bovine serum albumin (BSA) in the albumin: gold
nanoparticle bioconjugates were investigated in detail by various spectroscopic techniques …

Characterization of flavonoid-protein interactions using fluorescence spectroscopy: Binding of pelargonidin to dairy proteins

IJ Arroyo-Maya, J Campos-Terán, A Hernández-Arana… - Food chemistry, 2016 - Elsevier
In this study, the interaction between the flavonoid pelargonidin and dairy proteins: β-
lactoglobulin (β-LG), whey protein (WPI), and caseinate (CAS) was investigated …

Interactions of human serum albumin with chlorogenic acid and ferulic acid

J Kang, Y Liu, MX Xie, S Li, M Jiang… - Biochimica et biophysica …, 2004 - Elsevier
The interactions of chlorogenic acid and ferulic acid with human serum albumin (HSA) have
been investigated by fluorescence and Fourier transformed infrared (FT-IR) spectrometry …

[HTML][HTML] Binding of serum albumins with bioactive substances–nanoparticles to drugs

S Naveenraj, S Anandan - Journal of Photochemistry and Photobiology C …, 2013 - Elsevier
The interactions of human and bovine serum albumins (HSA and BSA) with various drugs
and nanomaterials receive great attention in the recent years owing to their significant …

Theoretical and computational studies of dendrimers as delivery vectors

Y Ma - Chemical Society Reviews, 2013 - pubs.rsc.org
It is a great challenge for nanomedicine to develop novel dendrimers with maximum
therapeutic potential and minimum side-effects for drug and gene delivery. As delivery …

Dendrimers and derivatives as a potential therapeutic tool in regenerative medicine strategies—A review

JM Oliveira, AJ Salgado, N Sousa, JF Mano… - Progress in Polymer …, 2010 - Elsevier
Since the pioneering work dealing with the synthesis and physicochemical aspects of
dendrimers, a predictable and tunable set of compositions for therapeutic, scaffolding and …