Macrophages: the good, the bad, and the gluttony
Macrophages are dynamic cells that play critical roles in the induction and resolution of
sterile inflammation. In this review, we will compile and interpret recent findings on the …
sterile inflammation. In this review, we will compile and interpret recent findings on the …
The anti-inflammatory properties of phytochemicals and their effects on epigenetic mechanisms involved in TLR4/NF-κB-mediated inflammation
HA Saleh, MH Yousef, A Abdelnaser - Frontiers in immunology, 2021 - frontiersin.org
Innate immune response induces positive inflammatory transducers and regulators in order
to attack pathogens, while simultaneously negative signaling regulators are transcribed to …
to attack pathogens, while simultaneously negative signaling regulators are transcribed to …
[HTML][HTML] Tetrahedral framework nucleic acids-based delivery of microRNA-155 inhibits choroidal neovascularization by regulating the polarization of macrophages
X Qin, L Xiao, N Li, C Hou, W Li, J Li, N Yan, Y Lin - Bioactive materials, 2022 - Elsevier
Choroidal neovascularization (CNV) is a common pathological feature of various eye
diseases and an important cause of visual impairment in middle-aged and elderly patients …
diseases and an important cause of visual impairment in middle-aged and elderly patients …
Sex steroids and autoimmune rheumatic diseases: state of the art
In autoimmune rheumatic diseases, oestrogens can stimulate certain immune responses
(including effects on B cells and innate immunity), but can also have dose-related anti …
(including effects on B cells and innate immunity), but can also have dose-related anti …
MicroRNAs and long non-coding RNAs in the pathophysiological processes of diabetic cardiomyopathy: emerging biomarkers and potential therapeutics
The epidemic of diabetes mellitus (DM) necessitates the development of novel therapeutic
and preventative strategies to attenuate complications of this debilitating disease. Diabetic …
and preventative strategies to attenuate complications of this debilitating disease. Diabetic …
MIR155HG is a prognostic biomarker and associated with immune infiltration and immune checkpoint molecules expression in multiple cancers
L Peng, Z Chen, Y Chen, X Wang, N Tang - Cancer medicine, 2019 - Wiley Online Library
In recent years, immune checkpoint inhibitor has achieved remarkable success in multiple
cancer treatment. However, how to pre‐judge which patients are suitable for immune …
cancer treatment. However, how to pre‐judge which patients are suitable for immune …
MicroRNA-155 and antiviral immune responses
A Jafarzadeh, A Naseri, L Shojaie, M Nemati… - International …, 2021 - Elsevier
The microRNA, miR-155 regulates both adaptive and innate immune responses. In viral
infections, miR-155 can affect both innate immunity (interferon response, natural killer cell …
infections, miR-155 can affect both innate immunity (interferon response, natural killer cell …
miR-221-3p drives the shift of M2-macrophages to a pro-inflammatory function by suppressing JAK3/STAT3 activation
L Quero, AN Tiaden, E Hanser, J Roux, A Laski… - Frontiers in …, 2020 - frontiersin.org
Objectives: Macrophages are conventionally classified as pro-inflammatory (M1) and anti-
inflammatory (M2) functional types. There is evidence for a predominance of macrophages …
inflammatory (M2) functional types. There is evidence for a predominance of macrophages …
Clinical significance of miRNAs in autoimmunity
MicroRNAs (miRNAs) are evolutionally conserved, single-stranded RNAs that regulate gene
expression at the posttranscriptional level by disrupting translation. MiRNAs are key players …
expression at the posttranscriptional level by disrupting translation. MiRNAs are key players …